Official Full Name | JAK2 Janus kinase 2 |
Synonyms | JAK2; Janus kinase 2; tyrosine-protein kinase JAK2; JTK10; JAK-2; Janus kinase 2 (a protein tyrosine kinase); THCYT3; |
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|
JAK2 involved in several pathways and played different roles in them. We selected most pathways JAK2 participated on our site, such as AGE/RAGE pathway, ARMS-mediated activation, Adipocytokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with JAK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
AGE/RAGE pathway | ATF2; EGFR; MAPK14; DIAPH1; DDOST; TIRAP; LGALS3; CHUK; JUN; AGER |
ARMS-mediated activation | FGF8B; CSF2RA; SPTA1; SLC14A2; CSK; FGF18B; PSME3; NRG4; NRG3; SPNA2 |
Adipocytokine signaling pathway | IRS4; AKT3A; NFKBIAA; JAK2; NFKBIB; ACSBG1; RXRG; AKT2L; MAPK8; CAMKK2 |
Axon guidance | ABLIM3; RGS3; NFATC4; COL6A2; RAC2; CFL2; SDCBP; GDNF; FGFR1B; PEA15A |
BDNF signaling pathway | SYN1; MAP3K2; DOK5; YBX1; EIF4EBP1; EEF2; JAK2; CSNK2A1; EIF4E; GNB2L1 |
CXCR4-mediated signaling events | CRK; ADRBK1; PAG1; CFL1; GNA13; MAPKAP1; GNB2L1; JAK2; DNM1; BLK |
Chemokine signaling pathway | GM1987; GM13306; GNGT2; PARD3; STAT5B; VAV3; CCR1; STAT1; CXCR2; CXCL14 |
Cholinergic synapse | MAPK1; CHRNA4; CHRM1; GNG13; GNAQ; CHRM5; PRKACB; KCNQ1; KRAS; PIK3CG |
JAK2 has several biochemical functions, for example, ATP binding, SH2 domain binding, acetylcholine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by JAK2 itself. We selected most functions JAK2 had, and list some proteins which have the same functions with JAK2. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
ATP binding | STK32C; CHUK; KIF3A; RAD54L; EHD2; UBE2I; NLRP14; GM7168; NME4; CLK2B |
SH2 domain binding | INPPL1; ARHGAP5; KHDRBS2; TRPV4; NLK; SKAP1; LILRB1; CRK; SYP; PAG1 |
acetylcholine receptor binding | APP; RIC3; KCNS1; RAPSN; RER1; DLG4; NRXN1; UBXN2A; JAK2 |
growth hormone receptor binding | JAK2; Gh; JAK1; SOCS2; GH1; TYK2 |
heme binding | CYP21A2; DUOX2; CYP1B1; CYP4F11; CYP7A1; HBAE1; MFSD7C; CYP19A1B; CYP4F14; MB |
histone binding | H3F3A; ZMYND11; BAZ2A; CTSL1; SUPT6H; PRKCBP1L; CHD2; HINFP; WDTC1; RCC1 |
histone kinase activity (H3-Y41 specific) | JAK2 |
insulin receptor substrate binding | PRKCD; INSR; GRB2; INSRB; PIK3R1; IGF1RA; PIK3CB; PRKCZ; IGF1R; INSRR |
interleukin-12 receptor binding | JAK2; IL12A; IL12BA; IL12B |
non-membrane spanning protein tyrosine kinase activity | YRK; LCK; RIPK2; SYK; TNK2; ABL2; WEE2; BMX; DYRK1A; JAK2A |
peptide hormone receptor binding | RUNDC3A; PTHLH; FYN; LEP; NPPA; ADCYAP1; JAK2; NPPC; PTPN11; PTH |
phosphatidylinositol 3-kinase binding | IGF1RB; BECN1; IRS1; ATP1A1; DAB1; FYN; FLT3; HCST; IGF1R; IRS4 |
protein C-terminus binding | VIM; ZBTB16; PCGF1; NPAT; PIAS3; SNX17; SIRT1; JAK2; NEIL1; PDZD11 |
protein binding | STX3; AMFR; LHX4; POLR1B; CHRAC1; PSMB9; URI1; SPTSSA; LANCL1; HYPM |
protein kinase activity | RIPK1L; EPHA4; EPHA1; DCLK2; SRPK1A; MAP3K12; GC3; CDK8; PAK4; MMD2 |
protein kinase binding | LLGL1; SLC12A4; HDAC4; RFFL; H2AFY; BCAR1; ERRFI1; CDK5RAP2; AXIN1; PAK2 |
protein tyrosine kinase activity | JAK3; MET; TESK1; EPHA2A; HCK; ZAP70; ERBB4A; MATK; PTK2BB; MAP2K4 |
receptor binding | APOL2; ANKRD13C; ACOX3; TENM2; EDA; EFNA1; PLAUR; WNT11R; CLCF1; GLA |
type 1 angiotensin receptor binding | GNA13A; BDKRB2; ARRB2; GNB1; ARAP1; TYK2; GNA13B; GNA13; AGT; JAK2 |
JAK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JAK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of JAK2.
PTPN1; CSF2RB; MPL; SH2B1; saicar; EGFR; PKM
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2023 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy