jak2

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jak2

Official Full Name JAK2 Janus kinase 2
Synonyms JAK2; Janus kinase 2; tyrosine-protein kinase JAK2; JTK10; JAK-2; Janus kinase 2 (a protein tyrosine kinase); THCYT3;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Human cells
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • DYKDDDDK
    • Flag
    • GST
    • His
    • MBP
    • Myc/DDK
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human JAK2-151H Recombinant Human JAK2 Protein, DYKDDDDK-tagged Human cells DYKDDDDK
    Human JAK2-01H Recombinant Human JAK2 Protein, His-tagged E. coli His
    Human JAK2-1420H Recombinant Human AMPX Protein, His-tagged Insect Cell His
    Human JAK2-157H Recombinant Human JAK2 protein, His/MBP-tagged E.coli His/MBP
    Human JAK2-158H Recombinant Human JAK2 protein, His/MBP-tagged E.coli His/MBP
    Human JAK2-2487H Recombinant human Jak2, His-tagged E.coli His
    Human JAK2-250H Recombinant Human JAK2 Mammalian Cell His
    Human JAK2-254H Recombinant Human JAK2 Protein, His-tagged E.coli His
    Human JAK2-26H Recombinant Human JAK2 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human JAK2-27628TH Recombinant Human JAK2, His-tagged His
    Human JAK2-27629TH Recombinant Human JAK2, His-tagged His
    Human JAK2-28H Recombinant Human JAK2 Protein, His-tagged E.coli His
    Human JAK2-336H Recombinant Human JAK2 protein, GST-tagged Insect Cell GST
    Human JAK2-3372H Recombinant Human JAK2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human JAK2-532H Recombinant Human Janus Kinase 2, His-tagged Sf9 Insect Cell His
    Human JAK2-5439H Recombinant Human Janus Kinase 2, GST-tagged Insect Cell GST
    Human JAK2-5441H Recombinant Human Janus Kinase 2, GST-His-tagged Sf9 Insect Cell GST/His
    Human JAK2-57H Recombinant Human JAK2 protein, Flag-tagged, Biotinylated Insect Cell Flag
    Human JAK2-598H Recombinant Human JAK2 protein, His-tagged E.coli His
    Human JAK2-81H Recombinant Human JAK2, GST-tagged Sf9 Insect Cell GST
    Mouse Jak2-255M Recombinant Mouse Jak2 Protein, His-tagged E.coli His
    Mouse Jak2-3627M Recombinant Mouse Jak2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat Jak2-257R Recombinant Rat Jak2 Protein, His-tagged E.coli His
    Rat JAK2-3136R Recombinant Rat JAK2 Protein Mammalian Cell His
    Rhesus Macaque JAK2-2327R Recombinant Rhesus monkey JAK2 Protein, His-tagged Mammalian Cell His
    Chicken JAK2-2252C Recombinant Chicken JAK2 Mammalian Cell His

    jak2 involved in several pathways and played different roles in them. We selected most pathways jak2 participated on our site, such as AGE/RAGE pathway, ARMS-mediated activation, Adipocytokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with jak2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    AGE/RAGE pathway JUN; TIRAP; LGALS3; MAPK14; JAK2; AGER; MMP13; DDOST; DIAPH1; EGFR
    ARMS-mediated activation LAMTOR2; NETO2; JAK1; CSF2RA; FRS2B; SPNA1; PHB; PSME3; PEA15A; SPTB
    Adipocytokine signaling pathway PRKAG2; SLC2A1; CAMKK1A; TNFRSF1B; PRKAG3; RXRA; NFKB1; POMC; RXRG; CPT1C
    Axon guidance KIF4; PPP3R1; SEMA3E; EFNB2; DUSP5; GNAI2; EFNB1; TRPC3; EPHA4; SCN3B
    BDNF signaling pathway CDK5; CNR1; MAP3K2; CSNK2A1P; IGF2BP1; SYN1; EEF2; CDKL5; DOK5; JAK2
    CXCR4-mediated signaling events BLK; CFL1; MAPKAP1; JAK2; GNA13; ARR3; CSK; CRK; ADRBK1; GNB2L1
    Chemokine signaling pathway GNG4; SRC; CXCL16; PRKCB; NFKBIB; NFKBIA; CCL1; RAF1; ARRB2; PIK3R3
    Cholinergic synapse CAMK2B; ATF4; CAMK2D; SLC5A7; MAPK3; CAMK4; CHRM4; PRKCG; PRKACA; CHRNA7

    jak2 has several biochemical functions, for example, ATP binding, SH2 domain binding, acetylcholine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by jak2 itself. We selected most functions jak2 had, and list some proteins which have the same functions with jak2. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding RPS6KB1B; NAT10; MCM8; NOD1; ACTR1B; TNIK; SRPK1A; ATP1A3A; EPHA10; XRCC5
    SH2 domain binding DLC1; SRC; SKAP1; LAT2; DAG1; SHCBP1; SYP; SH3PXD2B; SIT1; CTR9
    acetylcholine receptor binding APP; JAK2; RIC3; RAPSN; DLG4; RER1; NRXN1; KCNS1; UBXN2A
    growth hormone receptor binding JAK2; TYK2; JAK1; GH1; Gh; SOCS2
    heme binding CYP2K6; CYP26B1; NOS1; CYP2P8; CYP1A2; CYP4B1; CYP2D26; CYP46A1.3; HBZ; CYP17A1
    histone binding PIH1D1; SERPINB1A; SMARCA2; PRMT6; NCAPD3; NFKBIL2; NCL; HIST1H4C; NASP; SFMBT1
    histone kinase activity (H3-Y41 specific) JAK2
    insulin receptor substrate binding IGF1R; PIK3CA; PIK3CB; PRKCZ; INSRA; PTPN11; GRB2; PRKCD; JAK2; INSRR
    interleukin-12 receptor binding IL12B; IL12A; JAK2; IL12BA
    non-membrane spanning protein tyrosine kinase activity PTK6; SYK; PTK2AB; PTK2BB; FYNA; STK16; SRMS; TEC; STYK1; PKDCC
    peptide hormone receptor binding NPPC; PTHLH; JAK2; LEP; PTPN11; PTHLHA; FYN; NPPA; PTH; RUNDC3A
    phosphatidylinositol 3-kinase binding IRS4; IRS2; BECN1; INSRA; FYN; INSRB; ATP1A1; FLT3; IGF1R; PDGFRB
    protein C-terminus binding HIC2; EFHC1; PRKAA1; SLC9A3R2; PLEKHB1; KCNJ11; NEIL1; MYO1C; OPRL1; BAIAP2
    protein binding PRRG2; MYH11; TMBIM6; APBB1IP; SELENBP1; AMHR2; CPEB4; KLK15; KLRK1; POP1
    protein kinase activity CAMK2G1; PINK1; ULK1A; NTRK2B; JAK2B; SGK2B; MAP2K2A; EEF2K; RPS6KA5; EPHB2B
    protein kinase binding PAX6; CALM2; CDC25C; KIF13B; DLG1L; CCNL2; CAMK2N1; RPTOR; TCF7L2; AGTR1A
    protein tyrosine kinase activity WEE2; PTK7; EK1; EPHA7; MAP2K6; IGF1RA; CSF1RA; BCR; ERBB2; TTK
    receptor binding LHB; WNT5B; RSPO3; TENC1; SERPINE1; RSPO1; CYTL1; TNFSF4; CSNK2B; FZD8
    type 1 angiotensin receptor binding ARAP1; GNA13; JAK2; AGT; GNB1; ARRB2; GNA13B; BDKRB2; TYK2; GNA13A

    jak2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with jak2 here. Most of them are supplied by our site. Hope this information will be useful for your research of jak2.

    PTPN1; CSF2RB; MPL; SH2B1; saicar; EGFR; PKM

    Rath, T; Billmeier, U; et al. From physiology to disease and targeted therapy: interleukin-6 in inflammation and inflammation-associated carcinogenesis. ARCHIVES OF TOXICOLOGY 89:541-554(2015).
    Lan, HN; Jiang, HL; et al. Development and Characterization of a Novel Anti-idiotypic Monoclonal Antibody to Growth Hormone, Which Can Mimic Physiological Functions of Growth Hormone in Primary Porcine Hepatocytes. ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 28:573-583(2015).

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