Active Recombinant Human LDL Protein, His-tagged

• Cat.No.: LDL-22H
• Product Overview: Recombinant Human Lipoprotein Lipase-LPL Protein (Ala28-Gly475) with a C-terminal 6-His tag was expressed in Chinese Hamster Ovary cell line.

Specification

• Species: Human
• Source: CHO
• Tag: His
• Protein Length: 28-475 a.a.
• Description: LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
• Bio-activity: Measured by its ability to hydrolyze 4-Nitrophenyl butyrate. The specific activity is >2,500 pmol/min/μg.
• Molecular Mass: 51 kDa
• N-terminal Sequence Analysis: Ala28
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  6 months from date of receipt, -70 centigrade as supplied.
  3 months, -70 centigrade under sterile conditions after opening.
• Storage Buffer: Supplied as a 0.2 μm filtered solution in Tris, NaCl, CHAPS and Glycerol.
• Shipping: The product is shipped with dry ice or equivalent.

Gene Information

• Gene Name: LPL lipoprotein lipase [ Homo sapiens (human) ]
• Official Symbol: LPL
• Synonyms: LPL; lipoprotein lipase; LIPD; HDLCQ11; lipoprotein lipase; EC 3.1.1.34
• Gene ID: 4023
• mRNA Refseq: NM_000237
• Protein Refseq: NP_000228
• MIM: 609708
• UniProt ID: P06858