Description : |
Ly6/PLAUR domain containing 8 (LYPD8), is a GPI-linked protein with structural similarity to the urokinase-type plasminogen activator receptor (uPAR). Mature human LYPD8 contains one uPAR/Ly6 domain and a Ser/Thr/Pro-rich (STP) region that may serve as a target for protease mediated shedding as has been shown for the related C4.4A/LYPD3 molecule. Mature human LYPD8 shares 40% amino acid sequence identity with mouse and rat LYPD8. |
Source : |
CHO |
Species : |
Human |
Tag : |
Fc |
Predicted N Terminal : |
Leu20 |
Form : |
Lyophilized from a 0.2 μm filtered solution in PBS. |
Bio-activity : |
Measured by its binding ability in a functional ELISA. When Recombinant Human LYPD8 Fc Chimera is coated at 2 µg/mL, Recombinant Human Galectin‑3 binds with a typical ED50 = 90-540 ng/mL. |
Molecular Mass : |
Predicted Molecular Mass: 48 kDa;SDS-PAGE: 85-100 kDa, reducing conditions. |
Endotoxin : |
<0.10 EU per 1 μg of the protein by the LAL method. |
Purity : |
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Storage : |
Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : |
Reconstitute at 500 μg/mL in PBS. |