Active Recombinant Human Mitogen-activated Protein Kinase-activated Protein Kinase 3, GST-tagged

• Cat.No.: MAPKAPK3-840H
• Product Overview: Human MAPKAPK3 (NM_004635) full-length recombinant protein with GST tag expressed in SF9 cells.

Specification

• Species: Human
• Source: Human
• Tag: GST
• Description: MAP kinase-activated protein kinase 3 is an enzyme that in humans is encoded by the MAPKAPK3 gene. This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)-activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells.
• Theoretical MW (kDa): 69
• Preparation Method: Insect cell (SF9) expression system.
• Purity: μ 90% by densitometry
• Activity: The specific activity was determined to be 636 nmol/min/mg as per Activity Assay Protocol.
• Application: SDS-PAGE; Functional Study
• Storage Buffer: In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol).
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Unitprot ID: Q16644
• Pathways: MAPK signaling pathway; VEGF signaling pathway; Signalling by NG
• Functions: ATP binding; MAP kinase kinase activity; nucleotide binding; protein serine/threonine kinase activity; transferase activity

Gene Information

• Gene Name: MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 [ Homo sapiens ]
• Official Symbol: MAPKAPK3
• Synonyms: MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3; 3PK; MAPKAP3; MAPKAP kinase 3; OTTHUMP00000210806; EC 2.7.11.1; MAPK-activated protein kinase 3; Chromosome 3p kinase
• Gene ID: 7867
• mRNA Refseq: NM_004635
• Protein Refseq: NP_004626
• MIM: 602130
• Chromosome Location: 3p21.3