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Active Recombinant Human MMP9 Q279R Protein, His-tagged

Cat.No. : MMP9-005H
Product Overview : Active recombinant human MMP9 Q279R protein (20-707) with a C-terminal His tag was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Source : HEK293
Species : Human
Tag : His
Bio-activity : Activation: This is a proform enzyme and requires activation prior to testing activity. Dilute the enzyme to 100 ng/mL in a solution containing 50 mM HEPES, pH 7.4, 10 mM CaCl2, 0.05% Brij-35, and 1mM APMA (amino-phenyl mercuric acetate). Incubate at 37 centigrade for 2 hours.
Molecular Mass : 77.8 kDa
Protein length : 20-707
Purity : ≥90%
Applications : Enzyme assay
Stability : ≥ 1 year
Storage : At -80 centigrade.
Storage Buffer : 40 mM Tris-HCl buffer, pH 8.0, with 110 mM sodium chloride, 2.2 mM potassium chloride, 200 mM imidazole, and 20% glycerol
Gene Name : MMP9 matrix metallopeptidase 9 [ Homo sapiens (human) ]
Official Symbol : MMP9
Synonyms : MMP9; matrix metallopeptidase 9; GELB; CLG4B; MMP-9; MANDP2; matrix metalloproteinase-9; macrophage gelatinase; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); type V collagenase; EC
Gene ID : 4318
mRNA Refseq : NM_004994
Protein Refseq : NP_004985
MIM : 120361
UniProt ID : P14780

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.



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