Active Recombinant Human MS4A1 protein, Fc-tagged

• Cat.No.: MS4A1-17H
• Product Overview: Recombinant Human MS4A1 (Ile 141 – Tyr 184) fussed with Fc fragment of human IgG1 tag at N-terminal was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: Ile 141 – Tyr 184
• Form: Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH7.5.Normally Mannitol or Trehalose are added as protectants before lyophilization.
• Bio-activity: Validated Rituximab binding in the SPR assay (Biacore T100) with the KD of 0.2uM.
• Molecular Mass: Has a calculated MW of 32.6 kDa. Protein migrates as 42 kDa in reduced SDS-PAGE due to glycosylation.
• Endotoxin: Less than 1.0 EU per μg of the rhCD20 by the LAL method.
• Purity: >95% purity as determined by SDS-PAGE of reduced rhCD20.
• Storage: Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4 centigrade-8 centigrade); After reconstitution under sterile conditions for 1 month (4 centigrade-8 centigrade) or 3 months (-20 centigrade to -70 centigrade).

Gene Information

• Gene Name: MS4A1 membrane-spanning 4-domains, subfamily A, member 1 [ Homo sapiens ]
• Official Symbol: MS4A1
• Synonyms: MS4A1; membrane-spanning 4-domains, subfamily A, member 1; CD20; B-lymphocyte antigen CD20; B1; Bp35; MS4A2; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1; S7; CVID5; LEU-16; MGC3969
• Gene ID: 931
• mRNA Refseq: NM_021950
• Protein Refseq: NP_068769
• MIM: 112210
• UniProt ID: P11836
• Chromosome Location: 11q12-q13.1
• Pathway: Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem
• Function: epidermal growth factor receptor binding