MS4A1 Protein

MS4A1

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MS4A1

Official Full Name membrane-spanning 4-domains, subfamily A, member 1
Background This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
Synonyms MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1;
    • Species :
    • Canis lupus familiaris (Dog) (Canis familiaris)
    • Cynomolgus
    • Cynomolgus Monkey
    • Ferret
    • Homo sapiens (Human)
    • Human
    • Monkey
    • Mouse
    • Mus musculus (Mouse)
    • Source :
    • Baculovirus-Insect cells
    • E. coli
    • E.coli
    • E.coli expression system
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Yeast
    • Tag :
    • Biotin
    • Fc
    • Flag
    • GFP
    • GST
    • His
    • His/Avi
    • SUMO
    • trxA
    • His-Avi
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    • N-His
    • N-His&GST
    • TrxA
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MS4A1-17H Active Recombinant Human MS4A1 protein, Fc-tagged HEK293 Fc Inquiry
    Human MS4A1-19H Active Recombinant Human MS4A1 Protein, TrxA-tagged E.coli TrxA Inquiry
    Human MS4A1-151H Active Recombinant Human MS4A1 protein, Flag-tagged HEK293 Flag Inquiry
    Human MS4A1-17HAF488 Active Recombinant Human MS4A1 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
    Human MS4A1-17HAF555 Active Recombinant Human MS4A1 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
    Human MS4A1-17HAF647 Active Recombinant Human MS4A1 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
    Human MS4A1-17HF Active Recombinant Human MS4A1 Protein, Fc-tagged, FITC conjugated HEK293 Fc
    Human MS4A1-18H Recombinant Human MS4A1 protein, His/trxA-tagged E.coli His/trxA Inquiry
    Human MS4A1-22H Recombinant Human MS4A1 protein, His-tagged HEK293 His Inquiry
    Mouse Ms4a1-4893M Recombinant Mouse Ms4a1 protein, His/SUMO-tagged E.coli His/SUMO Inquiry
    Mouse Ms4a1-4896M Recombinant Mouse Ms4a1 protein, His-tagged Yeast His Inquiry
    Mouse Ms4a1-4899M Recombinant Mouse Ms4a1 protein, His/GST-tagged E.coli His/GST Inquiry
    Human MS4A1-10H Recombinant Human MS4A1, GST-tagged Wheat Germ GST Inquiry
    Human MS4A1-11H Recombinant Human MS4A1 Wheat Germ N/A Inquiry
    Human MS4A1-16H Recombinant Human MS4A1, His-tagged E.coli His Inquiry
    Human MS4A1-826H Recombinant Human MS4A1, Biotin-Fc-tagged HEK293 Biotin/Fc Inquiry
    Human MS4A1-8530H Recombinant Human MS4A1, His-tagged Human Cell His Inquiry
    Mouse MS4A1-10113M Recombinant Mouse MS4A1 Protein Mammalian Cell His Inquiry
    Cynomolgus Monkey MS4A1-62C Recombinant Cynomolgus MS4A1, His tagged Human Cell Fc Inquiry
    Cynomolgus MS4A1-708C Recombinant Cynomolgus MS4A1 protein, His-tagged HEK293 His Inquiry
    Ferret MS4A1-09F Recombinant Ferret MS4A1, His tagged Human Cell His Inquiry
    Human MS4A1-1542HCL Recombinant Human MS4A1 cell lysate Human Cell N/A Inquiry
    Cynomolgus Monkey MS4A1-819CCL Recombinant Cynomolgus MS4A1 cell lysate Human Cell N/A Inquiry
    Ferret MS4A1-1848FCL Recombinant Ferret MS4A1 cell lysate Human Cell N/A Inquiry
    Ferret MS4A1-09FAF488 Recombinant Ferret MS4A1 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
    Ferret MS4A1-09FAF555 Recombinant Ferret MS4A1 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
    Ferret MS4A1-09FAF647 Recombinant Ferret MS4A1 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
    Ferret MS4A1-09FF Recombinant Ferret MS4A1 Protein, His-tagged, FITC conjugated HEK293 His
    Human MS4A1-1135H Recombinant Human MS4A1 Protein, His&GST-tagged E.coli N-His&GST Inquiry
    Mouse Ms4a1-1136M Recombinant Mouse Ms4a1 Protein, His-tagged E.coli N-His Inquiry
    Human MS4A1-118HFL Recombinant Full Length Human MS4A1 Protein, C-Flag-tagged Mammalian cells Flag Inquiry
    Human MS4A1-391H Recombinant Fluorescent Human MS4A1 Full Length protein(VLPs), GFP-tagged HEK293 GFP Inquiry
    Human MS4A1-3930H Recombinant Human MS4A1 full length protein(VLPs) HEK293 N/A Inquiry
    Human MS4A1-3931H Recombinant Human MS4A1 full length protein, His/Avi-tagged, Biotinylated HEK293 His/Avi Inquiry
    Human MS4A1-3932H Recombinant Human MS4A1 full length protein, His/Avi-tagged, Biotinylated(Nanodisc) HEK293 His/Avi Inquiry
    Human MS4A1-5471H Recombinant Human MS4A1 protein, His-tagged Yeast His Inquiry
    Mouse Ms4a1-5472M Recombinant Mouse Ms4a1 protein, His-tagged Yeast His Inquiry
    Monkey MS4A1-62CAF488 Recombinant Cynomolgus MS4A1 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
    Monkey MS4A1-62CAF555 Recombinant Cynomolgus MS4A1 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
    Monkey MS4A1-62CAF647 Recombinant Cynomolgus MS4A1 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
    Monkey MS4A1-62CF Recombinant Cynomolgus MS4A1 Protein, His-tagged, FITC conjugated HEK293 His
    Human MS4A1-7308HAF488 Recombinant Human MS4A1 Protein, His-tagged, Alexa Fluor 488 conjugated His
    Human MS4A1-7308HAF555 Recombinant Human MS4A1 Protein, His-tagged, Alexa Fluor 555 conjugated His
    Human MS4A1-7308HAF647 Recombinant Human MS4A1 Protein, His-tagged, Alexa Fluor 647 conjugated His
    Human MS4A1-7308HF Recombinant Human MS4A1 Protein, His-tagged, FITC conjugated His
    Homo sapiens (Human) RFL14830HF Recombinant Full Length Human B-Lymphocyte Antigen Cd20(Ms4A1)-Vlps (Active) Protein, His-Tagged E.coli expression system His Inquiry
    Canis lupus familiaris (Dog) (Canis familiaris) RFL16853CF Recombinant Full Length Dog B-Lymphocyte Antigen Cd20(Ms4A1) Protein, His-Tagged E.coli expression system His Inquiry
    Homo sapiens (Human) RFL31628HF Recombinant Full Length Human B-Lymphocyte Antigen Cd20(Ms4A1) Protein, His-Tagged E.coli expression system His Inquiry
    Mus musculus (Mouse) RFL3192MF Recombinant Full Length Mouse B-Lymphocyte Antigen Cd20(Ms4A1) Protein, His-Tagged E.coli expression system His Inquiry
    Human MS4A1-1649H Recombinant Human MS4A1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Human MS4A1-17HA Recombinant Human MS4A1 protein, Fc-tagged, APC labeled HEK293 Fc Inquiry
    Human MS4A1-17HP Recombinant Human MS4A1 protein, Fc-tagged, R-PE labeled HEK293 Fc Inquiry
    Human MS4A1-1933H Recombinant Human MS4A1 Protein, MYC/DDK-tagged HEK293 Myc/DDK Inquiry
    Human MS4A1-3928H Recombinant Human MS4A1 protein, His-tagged HEK293 His Inquiry
    Human MS4A1-3929H Recombinant Human MS4A1 full length protein, His-tagged(Nanodisc) HEK293 His Inquiry
    Human MS4A1-420H Recombinant Human MS4A1 protein, His-Avi-tagged E. coli His-Avi Inquiry
    Human MS4A1-470H Recombinant Human MS4A1 Protein (Ile141-Ser188), TrxA-tagged, Biotinylated E.coli TrxA Inquiry
    Human MS4A1-48392H Recombinant Human MS4A1 protein, His-tagged Baculovirus-Insect cells His Inquiry
    Mouse Ms4a1-830M Recombinant Mouse Ms4a1 Protein, MYC/DDK-tagged HEK293T MYC/DDK Inquiry

    MS4A1 involved in several pathways and played different roles in them. We selected most pathways MS4A1 participated on our site, such as Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with MS4A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hematopoietic cell lineage ITGB3; CD8A; GM2002; EPOR; CD1E, B2M; IL3RA; IL9R; HLA-DRA; IL3; Cd24a

    MS4A1 has several biochemical functions, for example, MHC class II protein complex binding, epidermal growth factor receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MS4A1 itself. We selected most functions MS4A1 had, and list some proteins which have the same functions with MS4A1. You can find most of the proteins on our site.

    Function Related Protein
    MHC class II protein complex binding HLA-DOA; MS4A1; PKM; HLA-DOB; ATP1B1; HSP90AB1; HLA-DMB; HLA-DRB1; CD81; HSP90AA1
    epidermal growth factor receptor binding VAV2; CBLC; SNX2; TNK2; EPGN; ERBB4; LINGO1B; FAM83B; VAV3; ARF4
    protein binding IQCB1; DOK1; CAP2; IL32; RTP3; NRP1B; TBX24; NAT8B; COL23A1; PARK7

    MS4A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MS4A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MS4A1.

    CCDC155; IGHM; IGHD; CREB3; xthA; tyrS

    Ai, J; Advani, A; et al. Current status of antibody therapy in ALL. BRITISH JOURNAL OF HAEMATOLOGY 168:471-480(2015).
    Winiarska, M; Bojarczuk, K; et al. Inhibitors of SRC kinases impair antitumor activity of anti-CD20 monoclonal antibodies. MABS 6:1300-1313(2014).

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