Active Recombinant Human Mstn

• Cat.No.: Mstn-911H
• Product Overview: Recombinant Human Mstn (Accession # O14793) Asp268-Ser376, fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Predicted N Terminal: Asp268
• Form: Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
• Bio-activity: Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340.The ED50 for this effect is typically 2-10 ng/mL.
• Molecular Mass: Recombinant Human Mstn has a calculated MW of 12.4 kDa. In SDS-PAGE migrates as 12 kDa, reducing conditions24 kDa, non-reducing conditions.
• Protein length: Asp268-Ser376
• Purity: >90%, by SDS-PAGE with silver staining.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: MSTN myostatin [ Homo sapiens ]
• Official Symbol: Mstn
• Synonyms: MSTN; myostatin; GDF8, growth differentiation factor 8; growth/differentiation factor 8; GDF-8; growth differentiation factor 8; GDF8; MSLHP
• Gene ID: 2660
• mRNA Refseq: NM_005259
• Protein Refseq: NP_005250
• MIM: 601788
• UniProt ID: O14793
• Chromosome Location: 2q32.1