Active Recombinant Human NME4 protein, His-tagged
Cat.No. : | NME4-196H |
Product Overview : | Recombinant human NME4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Description : | NME4, also known as nucleoside diphosphate kinase, mitochondrial, belongs to the NDK family. NME4 are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates. The enzymes are products of the nm23 gene family, which includes NME4. NME4 plays a major role in the synthesis of nucleoside triphosphates other than ATP. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.2M NaCl |
Bio-activity : | Specific activity is > 120 units/mg, and is defined as the amount of enzyme that convert 1.0 umole each of ATP and TDP to ADP and TTP per minute at pH 7.5 at 25C in a couple system with PK/LDH. |
Molecular Mass : | 19.6 kDa (176aa), confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MPSWTRERTL VAVKPDGVQR RLVGDVIQRF ERRGFTLVGM KMLQAPESVL AEHYQDLRRK PFYPALIRYMSSGPVVAMVW EGYNVVRASR AMIGHTDSAE AAPGTIRGDF SVHISRNVIH ASDSVEGAQR EIQLWFQSSE LVSWADGGQH SSIHPA |
Purity : | > 90% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | NME4 non-metastatic cells 4, protein expressed in [ Homo sapiens ] |
Official Symbol : | NME4 |
Synonyms : | NME4; non-metastatic cells 4, protein expressed in; nucleoside diphosphate kinase, mitochondrial; nm23 H4; NM23H4; NDK; NDPKD; NDP kinase D; NDP kinase, mitochondrial; nucleoside diphosphate kinase D; NDPK-D; nm23-H4; |
Gene ID : | 4833 |
mRNA Refseq : | NM_005009 |
Protein Refseq : | NP_005000 |
MIM : | 601818 |
UniProt ID : | O00746 |
Chromosome Location : | 16p13.3 |
Pathway : | Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Pyrimidine metabolism, organism-specific biosystem; Pyrimidine metabolism, conserved biosystem; |
Function : | ATP binding; kinase activity; metal ion binding; nucleoside diphosphate kinase activity; nucleoside diphosphate kinase activity; nucleotide binding; transferase activity; |
Products Types
◆ Recombinant Protein | ||
Nme4-4437M | Recombinant Mouse Nme4 Protein, Myc/DDK-tagged | +Inquiry |
NME4-5930H | Recombinant Human NME4 Protein, GST-tagged | +Inquiry |
NME4-2875R | Recombinant Rhesus Macaque NME4 Protein, His (Fc)-Avi-tagged | +Inquiry |
NME4-6111M | Recombinant Mouse NME4 Protein, His (Fc)-Avi-tagged | +Inquiry |
NME4-4713H | Recombinant Human NME4 Protein (Thr67-His185), N-His tagged | +Inquiry |
◆ Lysates | ||
NME4-3789HCL | Recombinant Human NME4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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