Active Recombinant Human NTF4 Protein

• Cat.No.: NTF4-089H
• Product Overview: Recombinant Human NTF4 Protein (130 aa) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
• Bio-activity: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/mL, corresponding to a specific activity of 2-5 x 104 units/mg.
• Molecular Mass: 14 kD as monomer, 28 kD as dimer
• Endotoxin: < 0.1 EU/μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: NTF4 neurotrophin 4 [ Homo sapiens (human) ]
• Official Symbol: NTF4
• Synonyms: NTF4; neurotrophin 4; NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5; neurotrophin-4; Names; neurotrophic factor 4; neurotrophic factor 5; neurotrophin 5 (neurotrophin 4/5); neurotrophin-5; neutrophic factor 4
• Gene ID: 4909
• mRNA Refseq: NM_006179
• Protein Refseq: NP_006170
• MIM: 162662
• UniProt ID: P34130