Active Recombinant Human NUAK2, GST-tagged
Cat.No. : | NUAK2-1068H |
Product Overview : | Recombinant full-length human NUAK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | NUAK2 or SNF1/AMP kinase-related kinase (SNARK) is a member of the NUAK family of SNF1-like kinase 2. NUAK2 is activated by muscle contraction and is a unique mediator of contraction-stimulated glucose transport in skeletal muscle. NUAK2 is involved in cellular stress responses linked to obesity and type 2 diabetes. NUAK2 shows kinase activity against a synthetic test peptide and the activity in keratinocytes is increased by AMP and 5-amino-4-imidazolecarboxamide riboside, implying that AMPK kinase-dependent pathway can activate NAUK2. Glucose deprivation also increases NAUK2 activity in baby hamster kidney fibroblasts. |
Source : | Sf9 insect cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 80 nmol/min/mg |
Molecular Mass : | ~110 kDa |
Protein length : | Full Length |
Purity : | >75% |
Applications : | Kinase Assay; Western Blot |
Stability : | 1 yr at -70oC from date of shipment. |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 ug/ul |
Gene Name : | NUAK2 NUAK family, SNF1-like kinase, 2 [ Homo sapiens (human) ] |
Official Symbol : | NUAK2 |
Synonyms : | NUAK2; NUAK family, SNF1-like kinase, 2; NUAK family SNF1-like kinase 2; FLJ90349; SNARK; SNF1/AMP activated protein kinase |
Gene ID : | 81788 |
mRNA Refseq : | NM_030952 |
Protein Refseq : | NP_112214 |
MIM : | 608131 |
UniProt ID : | Q9H093 |
Chromosome Location : | 1q32.1 |
Function : | ATP binding; metal ion binding; protein binding; protein serine/threonine kinase activity |
Products Types
◆ Recombinant Protein | ||
NUAK2-6239M | Recombinant Mouse NUAK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NUAK2-3767R | Recombinant Rat NUAK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NUAK2-27531TH | Recombinant Human NUAK2 | +Inquiry |
NUAK2-4106R | Recombinant Rat NUAK2 Protein | +Inquiry |
NUAK2-91H | Active Recombinant Human NUAK2, His-tagged(Mutant K85R) | +Inquiry |
◆ Lysates | ||
NUAK2-3664HCL | Recombinant Human NUAK2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket