Active Recombinant Human PDCD1 Protein
| Cat.No. : | PDCD1-01H |
| Product Overview : | Recombinant Human PDCD1 Protein was expressed in HEK293 cell |
- Specification
- Gene Information
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| Description : | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. |
| Source : | HEK293 |
| Species : | Human |
| Form : | Lyophilized |
| Bio-activity : | Measured by its binding ability in a functional ELISA. |
| Molecular Mass : | Expected molecular weight ~16 kD, observed molecular weight 30 kD in SDS-PAGE due to glycosylation of the protein. |
| Protein length : | Protein fragment |
| AA Sequence : | LDSPDRPWNP PTFSPALLVV TEGDNATFTC SFSNTSESFV LNWYRMSPSN QTDKLAAFPE DRSQPGQDCR FRVTQLPNGR DFHMSVVRAR RNDSGTYLCG AISLAPKAQI KESLRAELRV TERRAEVPTA HPSPSPRPAG QFQ |
| Endotoxin : | < 0.010 Eu/µg |
| Purity : | > 95 % SDS-PAGE. |
| Applications : | SDS-PAGE Functional Studies |
| Notes : | FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC PROCEDURES |
| Storage : | Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. Constituent: PBS Lyophilized from 0.2µm-filtered solution. This product is an active protein and may elicit a biological response in vivo, handle with caution. |
| Storage Buffer : | Lyophilized from 0.2µm-filtered solution. |
| Reconstitution : | Reconstitute 50µg vial with 100 µl sterile water to a concentration of 0.5 mg/ml. Add 1X PBS to the desired protein concentration. PBS containing at least 0.1% BSA should be used for further dilutions. |
| Shipping : | Shipped at 4°C. |
| Gene Name : | PDCD1 programmed cell death 1 [ Homo sapiens (human) ] |
| Official Symbol : | PDCD1 |
| Synonyms : | PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1 |
| Gene ID : | 5133 |
| mRNA Refseq : | NM_005018.3 |
| Protein Refseq : | NP_005009.2 |
| MIM : | 600244 |
| UniProt ID : | Q15116 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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