Active Recombinant Human PDCD1 Protein, Fc-His-tagged, PE-Labeled
| Cat.No. : | PDCD1-4688H |
| Product Overview : | PE-Labeled Recombinant Human Protein(Leu 25 - Gln 167), fused with Fc-His tag, was expressed in HEK293. |
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| Source : | HEK293 |
| Species : | Human |
| Tag : | His&Fc |
| Form : | Lyophilized from 0.22 μm filtered solution in PBS, 0.5% BSA, pH7.4. Normally trehalose is added as protectant before lyophilization. |
| Bio-activity : | Flow Cytometry assay shows that PE-Labeled Human PD-1, Fc,His Tag can bind to 293T cells overexpressing human PD-L1. 1 μL stock solution per million cells.FACS analysis shows that the binding of PE-Labeled Human PD-1, Fc,His Tag to 293T overexpressing PD-L1 was inhibited by increasing concentration of neutralizing anti-human PD-L1 antibody. The IC50 is 0.29 μg/mL. |
| Molecular Mass : | This protein carries a human IgG1 Fc tag at the C-terminus, followed by a polyhistidine tag.The protein has a calculated MW of 44.7 kDa. |
| Protein length : | Leu 25 - Gln 167 |
| Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please protect from light and avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
| Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
| Gene Name : | PDCD1 programmed cell death 1 [ Homo sapiens ] |
| Official Symbol : | PDCD1 |
| Synonyms : | PDCD1; programmed cell death 1; programmed cell death protein 1; CD279; PD1; protein PD-1; PD-1; SLEB2; hPD-1; hPD-l; |
| Gene ID : | 5133 |
| mRNA Refseq : | NM_005018 |
| Protein Refseq : | NP_005009 |
| MIM : | 600244 |
| UniProt ID : | Q15116 |
Products Types
| ◆ Lysates | ||
| PDCD1-2873HCL | Recombinant Human PDCD1 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewTimely antibody validation, a valuable asset for our laboratory.
Precise protein quantification, fundamental for maintaining data accuracy.
Dependable peptide synthesis, accelerates our peptide-based projects effectively.
Q&As (14)
Ask a questionPDCD1 modulates responses to viral infections, affecting T cell function and viral clearance.
PDCD1 modulates responses to viral infections, affecting T cell function and viral clearance.
PDCD1 helps develop immune tolerance, preventing overactive immune responses.
PDCD1 maintains a balance between immune response and autoimmunity, preventing self-reactivity.
PDCD1 contributes to T cell exhaustion in chronic diseases and cancers, reducing immune efficacy.
PDCD1 maintains a balance between immune response and autoimmunity, preventing self-reactivity.
PDCD1's role in immunotherapy is pivotal, as blocking PD-1 enhances anti-tumor responses.
PDCD1 contributes to T cell exhaustion in chronic diseases and cancers, reducing immune efficacy.
PDCD1 regulates T cell activity by inhibiting immune responses, crucial in immune checkpoints.
PDCD1's role in immunotherapy is pivotal, as blocking PD-1 enhances anti-tumor responses.
PDCD1 helps develop immune tolerance, preventing overactive immune responses.
Changes in PDCD1 signaling impact autoimmune disease progression, influencing immune system activity.
PDCD1 regulates T cell activity by inhibiting immune responses, crucial in immune checkpoints.
Changes in PDCD1 signaling impact autoimmune disease progression, influencing immune system activity.
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