Active Recombinant Human PDCD1 Protein, MIgG2a mFc-tagged, FITC conjugated
Cat.No. : | PDCD1-031HF |
Product Overview : | The FITC conjugated extracellular domain of human CD279 [PD-1] (NP_005009.2) (Leu25-Gln167) is fused to the N-terminus of the Fc region of mouse IgG2a.E351 |
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Description : | This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |
Source : | CHO |
Species : | Human |
Tag : | mFc |
Form : | Lyophilized |
Bio-activity : | Measured by its binding ability in a functional ELISA. |
Molecular Mass : | 46 kDa (monomer) |
AA Sequence : | Leu25-Gln167 |
Endotoxin : | < 0.06 EU/ μg as determined by LAL test. |
Purity : | > 98 % by SDS-PAGE under reducing conditions. |
Characteristic : | Disulfide-linked homodimer Labeled with FITC via amines Excitation source: 488 nm spectral line, argon-ion laser Excitation Wavelength: 488 nm Emission Wavelength: 535 nm |
Stability : | Stable for at least 1 year after receipt when stored at -20 centigrade. Working aliquots are stable for up to 3 months when stored at -20 centigrade. |
Concentration : | 100 μg/mL |
Storage Buffer : | Lyophilized from 0.2 μm filtered solution in PBS. |
Reconstitution : | Reconstitute at 100 μg/mL in sterile PBS. |
Gene Name : | PDCD1 programmed cell death 1 [ Homo sapiens ] |
Official Symbol : | PDCD1 |
Synonyms : | PDCD1; programmed cell death 1; programmed cell death protein 1; CD279; PD1; protein PD-1; PD-1; SLEB2; hPD-1; hPD-l; |
Gene ID : | 5133 |
mRNA Refseq : | NM_005018 |
Protein Refseq : | NP_005009 |
MIM : | 600244 |
UniProt ID : | Q15116 |
Products Types
◆ Lysates | ||
PDCD1-001RCL | Recombinant Rat PDCD1 cell lysate | +Inquiry |
PDCD1-2873HCL | Recombinant Human PDCD1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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