Active Recombinant Human PDE4D protein, GST-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Cat.No. : | PDE4D-10H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human PDE4D(2–507 aa) fused with GST tag at N-terminal was expressed in Insect cells. |
Description : | This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins. |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Form : | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% Glycerol and 16 mM Glutathione. |
Bio-activity : | ≥ 13,600 pmol/min/µg |
Molecular Mass : | 84 kDa |
Purity : | > 86% |
Unit Definition : | One unit is defined as the amount of enzyme that will convert 1 pmole of 3', 5'-cAMP to 5'-AMP per minute at 37 centigrade. |
Applications : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Storage : | >6 months at -80 centigrade. Avoid freeze/thaw cycles. |
Concentration : | 0.27 mg/ml |
Figure : |
![]() |
Gene Name : | PDE4D phosphodiesterase 4D, cAMP-specific [ Homo sapiens ] |
Official Symbol : | PDE4D |
Synonyms : | PDE4D; phosphodiesterase 4D, cAMP-specific; DPDE3, phosphodiesterase 4D, cAMP specific (dunce (Drosophila) homolog phosphodiesterase E3); cAMP-specific 3,5-cyclic phosphodiesterase 4D; phosphodiesterase E3 dunce homolog (Drosophila); cAMP-specific phosphodiesterase PDE4D6; phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila); DPDE3; PDE43; STRK1; HSPDE4D; PDE4DN2; FLJ97311; DKFZp686M11213; |
Gene ID : | 5144 |
mRNA Refseq : | NM_001197221 |
Protein Refseq : | NP_001184150 |
MIM : | 600129 |
UniProt ID : | Q08499 |
Chromosome Location : | 5q12 |
Pathway : | DARPP-32 events, organism-specific biosystem; G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Morphine addiction, organism-specific biosystem; Morphine addiction, conserved biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; |
Function : | 3,5-cyclic-AMP phosphodiesterase activity; 3,5-cyclic-nucleotide phosphodiesterase activity; cAMP binding; drug binding; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity; |
◆ Recombinant Protein
Pde4d-4747M | Recombinant Mouse Pde4d Protein, Myc/DDK-tagged | +Inquiry |
PDE4D-303H | Recombinant Human PDE4D Protein, His/GST-tagged | +Inquiry |
PDE4D-28756TH | Recombinant Human PDE4D | +Inquiry |
PDE4D-4332R | Recombinant Rat PDE4D Protein | +Inquiry |
PDE4D-478H | Recombinant Human PDE4D, GST-tagged, Active | +Inquiry |
|
◆ Lysates
PDE4D-3350HCL | Recombinant Human PDE4D 293 Cell Lysate | +Inquiry |
|
Pde10aPDE11APDE1APDE1BPde1cPDE2APDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE6BPDE6CPDE6DPDE7APDE7BPDE8APDE9APDE4DIPPDE12PDE6APDE8BPDE6GPDE6H
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2023 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy