PDE4D-10H
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant Human PDE4D(2–507 aa) fused with GST tag at N-terminal was expressed in Insect cells.
Description :
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
Source :
Insect cells
Species :
Human
Tag :
GST
Form :
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% Glycerol and 16 mM Glutathione.
Bio-activity :
≥ 13,600 pmol/min/µg
Molecular Mass :
84 kDa
Purity :
> 86%
Unit Definition :
One unit is defined as the amount of enzyme that will convert 1 pmole of 3', 5'-cAMP to 5'-AMP per minute at 37 centigrade.
Applications :
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage :
>6 months at -80 centigrade. Avoid freeze/thaw cycles.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.