Active Recombinant Human PIM2, GST-tagged
Cat.No. : | PIM2-1456H |
Product Overview : | Recombinant full-length human PIM2 was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | PIM2 is a serine threonine kinase that is present in all tissues, being most abundant in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. It is highly expressed in human leukemic, lymphoma and colorectal adenocarcinoma cell lines. This suggests a role for PIM2 in proliferating cells as well as during meiosis. Similar to PIM1, PIM2 also acts as a pro-survival kinase and BAD protein is a legitimate PIM2 substrate. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 305 nmol/min/mg |
Molecular Mass : | ~61 kDa |
Protein length : | Full length |
Purity : | >95% |
Applications : | Kinase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | PIM2 pim-2 oncogene [ Homo sapiens ] |
Official Symbol : | PIM2 |
Synonyms : | PIM2; pim-2 oncogene; serine/threonine-protein kinase pim-2; pim-2h; serine/threonine protein kinase pim-2; proto-oncogene Pim-2 (serine threonine kinase); |
Gene ID : | 11040 |
mRNA Refseq : | NM_006875 |
Protein Refseq : | NP_006866 |
MIM : | 300295 |
UniProt ID : | Q9P1W9 |
Chromosome Location : | Xp11.23 |
Pathway : | Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; |
Function : | ATP binding; nucleotide binding; protein serine/threonine kinase activity; |
Products Types
◆ Recombinant Protein | ||
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PIM2-6746M | Recombinant Mouse PIM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PIM2-0921H | Recombinant Human PIM2 Protein (M1-P311), Tag Free | +Inquiry |
PIM2-0922H | Recombinant Human PIM2 Protein (M1-P311), His tagged | +Inquiry |
◆ Lysates | ||
PIM2-3180HCL | Recombinant Human PIM2 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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