Active Recombinant Human PPIB
Cat.No. : | PPIB-8314H |
Product Overview : | Cyclophilin B Human Recombinant produced in E.coli is a single, non-glycosylated,polypeptide chain containing 192 amino acids (26-216) and having a molecular mass of 21.2 kDa. PPIB is purified by chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. |
Source : | E.coli |
Species : | Human |
Form : | 1 mg/ml solution containing 20 mM Tris 8.0, 20 mM NaCl, 0.5mM DTT and 10% glycerol. |
Bio-activity : | Specific activity is 170 nmoles/min/ug, and is defined as the amount of enzyme that cleave 1umole of suc-AAFP-pNA per minute at 1C in Tris-Hcl pH8.0 using chymotrypsin. |
AA Sequence : | MLLPGPSAAD EKKKGPKVTV KVYFDLRIGD EDVGRVIFGL FGKTVPKTVD NFVALATGEKGFGYKNSKFH RVIKDFMIQG GDFTRGDGTG GKSIYGERFP DENFKLKHYG PGWVSMANAGKDTNGSQFFI TTVKTAWLDG KHVVFGKVLE GMEVVRKVES TKTDSRDKPL KDVIIADCGK IEVEKPFAIA KE. |
Purity : | Greater than 95.0% as determined by RP-HPLC and analysis by SDS-PAGE |
Notes : | For research use only. |
Storage : | PPIase Human Recombinant although stable at 4 ℃ for weeks, should be stored desiccated below -18 ℃. Please prevent freeze/thaw cycles. |
Gene Name : | PPIB peptidylprolyl isomerase B (cyclophilin B) [ Homo sapiens ] |
Official Symbol : | PPIB |
Synonyms : | PPIB; peptidylprolyl isomerase B (cyclophilin B); peptidyl-prolyl cis-trans isomerase B; CYPB; OI9; |
Gene ID : | 5479 |
mRNA Refseq : | NM_000942 |
Protein Refseq : | NP_000933 |
MIM : | 123841 |
UniProt ID : | P23284 |
Chromosome Location : | 15q21-q22 |
Pathway : | Syndecan-1-mediated signaling events, organism-specific biosystem; |
Function : | isomerase activity; peptide binding; peptidyl-prolyl cis-trans isomerase activity; protein binding; unfolded protein binding; |
Products Types
◆ Recombinant Protein | ||
PPIB-3362R | Recombinant Rhesus Macaque PPIB Protein, His (Fc)-Avi-tagged | +Inquiry |
PPIB-4260R | Recombinant Rat PPIB Protein, His (Fc)-Avi-tagged | +Inquiry |
PPIB-777H | Recombinant Human PPIB Protein | +Inquiry |
PPIB-2673H | Recombinant Human PPIB Protein, MYC/DDK-tagged | +Inquiry |
PPIB-63H | Active Recombinant Human PPIB Protein | +Inquiry |
◆ Lysates | ||
PPIB-2460HCL | Recombinant Human PPIB cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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