Active Recombinant Human PTPN2 protein

• Cat.No.: PTPN2-2196H
• Product Overview: Active Recombinant Human PTPN2 protein(P17706-1) (Met 1-Asn 314) was expressed and purified in Insect Cells, with two additional amino acids (Gly & Pro ) at the N-terminus.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Non
• Protein Length: 1-314 aa
• Form: Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0.
• Bio-activity: Measured by its ability to dephosphorylate a phosphotyrosine residue in an EGF receptor 988-998 phosphopeptide substrate. The specific activity is > 30 μmoles/min/mg.
• Molecular Mass: The secreted recombinant human PTPN2 consists of 316 amino acids and predicts a molecular mass of 36.8 KDa. The apparent molecular mass of the protein is approximately 37 KDa in SDS-PAGE under reducing conditions due to glycosylation.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: PTPN2 protein tyrosine phosphatase, non-receptor type 2 [ Homo sapiens ]
• Official Symbol: PTPN2
• Synonyms: PTPN2; protein tyrosine phosphatase, non-receptor type 2; PTPT; tyrosine-protein phosphatase non-receptor type 2; TC PTP; TCELLPTP; TCPTP; T-cell protein tyrosine phosphatase; PTN2; TC-PTP
• Gene ID: 5771
• mRNA Refseq: NM_001207013
• Protein Refseq: NP_001193942
• MIM: 176887
• UniProt ID: P17706