Active Recombinant Human RXRB Protein, GST tagged

• Cat.No.: RXRB-32H
• Product Overview: Recombinant human Retinoid X Receptor beta Ligand Binding Domain, GST-tagged (amino acids 295-533; NP_068811) is expressed in insect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Protein Length: 295-533 aa
• Description: This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Form: 50 mM Tris (pH 7.5), 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X–100, 10 mM DTT and 50% Glycerol.
• Molecular Mass: 54.5 kDa. Calculated from the protein sequence(s).
• Purity: 85% as determined by a SDS-PAGE gel stained with SimplyBlue SafeStain.
• Storage: If properly stored in its original container at -80 centigrade, this product is guaranteed for 6 months from date of purchase. Mix gently, do not vortex. Do NOT make single use aliquots.
• Concentration: 0.57 mg/mL total protein as measured using the Bradford protein assay with BSA as a standard. Calculated 10,500 nM.
• Shipping: Dry ice

Gene Information

• Gene Name: RXRB retinoid X receptor beta [ Homo sapiens (human) ]
• Official Symbol: RXRB
• Synonyms: RXRB; retinoid X receptor beta; NR2B2; DAUDI6; RCoR-1; RXRbeta; H-2RIIBP; RXR-beta; retinoic acid receptor RXR-beta; MHC class I promoter binding protein; nuclear receptor subfamily 2 group B member 2
• Gene ID: 6257
• mRNA Refseq: NM_021976
• Protein Refseq: NP_068811
• MIM: 180246
• UniProt ID: P28702