Active Recombinant Human S100A8 (Met1-Glu93) and S100A9 (Thr2-Pro114) Heterodimer Protein
Cat.No. : | S100A8/S100A9-13H |
Product Overview : | Recombinant human S100A8 (Met1-Glu93) and S100A9 (Thr2-Pro114) Heterodimer protein without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | E. coli |
Species : | Human |
Form : | Noncovalently-linked heterodimer |
Bio-activity : | Measured by its ability to induce IL-6 secretion by A375 human melanoma cells. The ED50 for this effect is 1.5-6 μg/mL. |
Molecular Mass : | Predicted Molecular Mass: 11 kDa (S100A8) & 13 kDa (S100A9) SDS-PAGE: 9 kDa (S100A8) & 13 kDa (S100A9), reducing conditions |
Protein Length : | Met1-Glu93 (S100A8) & Thr2-Pro114 (S100A9) |
N-terminal Sequence Analysis : | Met1 (S100A8) & Thr2 (S100A9) |
Endotoxin : | < 0.10 EU/μg of the protein by the LAL method. |
Purity : | > 95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS and DTT. |
Reconstitution : | Reconstitute at 500 μg/mL in sterile PBS. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | S100A8 S100 calcium binding protein A8 [ Homo sapiens (human) ] |
Official Symbol : | S100A8 |
Synonyms : | S100A8; S100 calcium binding protein A8; CAGA, CFAG, S100 calcium binding protein A8 (calgranulin A), S100 calcium binding protein A8 (calgranulin A); protein S100-A8; 60B8AG; CGLA; MRP8; P8; MRP-8; calgranulin A; calgranulin-A; cystic fibrosis antigen; calprotectin L1L subunit; urinary stone protein band A; leukocyte L1 complex light chain; migration inhibitory factor-related protein 8; S100 calcium-binding protein A8 (calgranulin A); MIF; NIF; CAGA; CFAG; L1Ag; CP-10; MA387; |
Gene ID : | 6279 |
mRNA Refseq : | NM_002964 |
Protein Refseq : | NP_002955 |
MIM : | 123885 |
UniProt ID : | P05109 |
Products Types
◆ Recombinant Protein | ||
S100A8-1510M | Recombinant Mouse S100A8 Protein (2-89 aa), His-tagged | +Inquiry |
S100A8-12H | Recombinant Human S100A8 Protein (Leu2-Glu93), N-His-tagged | +Inquiry |
S100a8-127M | Recombinant Mouse S100a8 Protein, His-tagged | +Inquiry |
S100A8-1013H | Active Recombinant Human Calprotectin Protein | +Inquiry |
S100A8-2709H | Recombinant Human S100A8 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
S100A8-685HCL | Recombinant Human S100A8 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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