Active Recombinant Human SAE1/SAE2

• Cat.No.: SAE1-104H
• Product Overview: Recombinant Human SUMO E1 enzyme is a heterodimer of His-tagged SAE1 and untagged SAE2, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Form: Liquid. 20mM Tris, 150 mM NaCl, 2 mM βME, 10% glycerol
• Bio-activity: 100nM is used for in vitro conjugation
• Molecular Mass: 39 kDa and 73 kDa
• Purity: >80%
• Storage: Store at -80℃. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: SAE1 SUMO1 activating enzyme subunit 1 [ Homo sapiens ]
• Official Symbol: SAE1
• Synonyms: SAE1; SUMO1 activating enzyme subunit 1; SUMO-activating enzyme subunit 1; activator Of sumo 1; AOS1; FLJ3091; Sua1; activator of SUMO1; SUMO-1 activating enzyme subunit 1; sentrin/SUMO-activating protein AOS1; SUMO-1 activating enzyme E1 N subunit; ubiquitin-like 1-activating enzyme E1A; ubiquitin-like protein SUMO-1 activating enzyme; SUA1; UBLE1A; HSPC140
• Gene ID: 10055
• mRNA Refseq: NM_001145713
• Protein Refseq: NP_001139185
• MIM: 613294
• UniProt ID: Q9UBE0
• Chromosome Location: 19q13.32
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem
• Function: ATP-dependent protein binding; contributes_to SUMO activating enzyme activity; enzyme activator activity; ligase activity; nucleotide binding; protein C-terminus binding; protein binding; protein heterodimerization activity; protein heterodimerization activity; ubiquitin activating enzyme activity