Active Recombinant Human SDC4, His-tagged

• Cat.No.: SDC4-19H
• Product Overview: Recombinant Human SDC4 (Glu19-Glu145) fused with 6­His tag at C­terminal, was expressed in Mouse NSO Cells.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: His
• Protein Length: 19-145 a.a.
• Description: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22.
• Predicted N Terminal: Glu19
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA. Immobilized rhSyndecan-4 at 500 ng/mL (100 µL/well) can bind rhFGF-basic with a linear range of 0.1 - 10 ng/mL.
• Molecular Mass: 14.7 kDa
• Endotoxin: < 1.0 EU per 1 μg of the protein by the LAL method.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 °C to -70 °C as supplied. 1 month, 2 °C to 8 °C under sterile conditions after reconstitution. 3 months, -20 °C to -70 °C under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 100 µg/mL in sterile PBS.

Gene Information

• Gene Name: SDC4 syndecan 4 [ Homo sapiens (human) ]
• Official Symbol: SDC4
• Synonyms: SDC4; SYND4; syndecan 4; syndecan-4; amphiglycan; ryudocan amphiglycan; ryudocan core protein; syndecan proteoglycan 4; syndecan 4 (amphiglycan, ryudocan)
• Gene ID: 6385
• mRNA Refseq: NM_002999
• Protein Refseq: NP_002990
• MIM: 600017
• UniProt ID: P31431
• Chromosome Location: 20q12
• Pathway: A tetrasaccharide linker sequence is required for GAG synthesis; Cell adhesion molecules (CAMs); ECM-receptor interaction
• Function: cytoskeletal protein binding; fibronectin binding; protein binding