Active Recombinant Human SIGLEC10 Protein (ECD), mFc-tagged

• Cat.No.: SIGLEC10-03H
• Product Overview: Recombinant human SIGLEC10 (NP_149121.2) (Met17-Thr546) (extra-cellular domain) with the Fc region of mouse IgG2a at the C-terminus was expressed HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: mFc
• Protein Length: 763
• Description: SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6.
• Form: Lyophilized
• Bio-activity: Testing in progress
• Molecular Mass: 84.60 kDa
• N-terminal Sequence Analysis: Met 17
• Endotoxin: < 1.0 EU/μg protein as determined by the LAL method.
• Purity: > 95 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Lyophilized from sterile PBS, pH 7.4
  Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.

Gene Information

• Gene Name: SIGLEC10 sialic acid binding Ig like lectin 10 [ Homo sapiens (human) ]
• Official Symbol: SIGLEC10
• Synonyms: SIGLEC10; sialic acid binding Ig like lectin 10; SLG2; PRO940; SIGLEC-10; sialic acid-binding Ig-like lectin 10; sialic acid binding Ig-like lectin 10 Ig-like lectin 7; siglec-like gene 2; siglec-like protein 2
• Gene ID: 89790
• mRNA Refseq: NM_033130
• Protein Refseq: NP_149121
• MIM: 606091
• UniProt ID: Q96LC7