- Human(6)
Recombinant Human SIGLEC10 protein, His-tagged
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| Cat.No. : | SIGLEC10-059H |
| Product Overview : | Human Siglec-2/CD22 is expressed from mammalian with a His tag and Avi Tag at the C-terminal. It contains Asp20-Arg687. |
| Description : | Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | His |
| Form : | Supplied as 0.22um filtered solution in 20mM PB, 150mM Nal, 25mM Arginine(pH 7.4). |
| Molecular Mass : | The protein has a predicted MW of 78.1 kDa. Due to glycosylation, the protein migrates to 100- 115KDa based on Bis-Tris PAGE result. |
| Protein length : | It contains Asp20-Arg687. |
| Endotoxin : | Less than 0.05EU per ug by the LAL method. |
| Purity : | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
| Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents. |
| Tris-Bis PAGE : |
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| HPLC data : |
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| ELISA data : |
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| Gene Name : | SIGLEC10 sialic acid binding Ig-like lectin 10 [ Homo sapiens ] |
| Official Symbol : | SIGLEC10 |
| Synonyms : | siglec 10; siglec-10; siglec10; Sialic acid-binding Ig-like lectin 10; Siglec-like protein 2; SLG2 |
| Gene ID : | 89790 |
| mRNA Refseq : | NM_001171156 |
| Protein Refseq : | NP_001164627 |
| MIM : | 606091 |
| UniProt ID : | Q96LC7 |
◆ Recombinant Protein
| SIGLEC10-1059H | Recombinant Human SIGLEC10 protein, His & S-tagged | +Inquiry |
| SIGLEC10-967H | Recombinant Human SIGLEC10 protein, Fc-Avi-tagged | +Inquiry |
| SIGLEC10-331H | Recombinant Human SIGLEC10 protein, Mouse IgG2a Fc-tagged, low endotoxin | +Inquiry |
| SIGLEC10-907HB | Recombinant Human SIGLEC10 protein, Fc-Avi-tagged, Biotinylated | +Inquiry |
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◆ Lysates
| SIGLEC10-1849HCL | Recombinant Human SIGLEC10 293 Cell Lysate | +Inquiry |
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SIGLEC6SIGLEC9SIGLEC1SIGLEC10SIGLEC12SIGLEC7SIGLEC8SIGLEC14SIGLEC5SIGLEC11Siglec15
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