Active Recombinant Human SLAMF7 protein, His-tagged
Cat.No. : | SLAMF7-1281H |
Product Overview : | Recombinant Human SLAMF7/CD319 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ser23-Met226) of human SLAMF7/CD319 (Accession #NP_067004.3) fused with a 6×His tag at the C-terminus. |
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Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human SLAMF7 at 2 μg/mL (100 μL/well) can bind Anti-SLAMF7 antibody with a linear range of 40-120 ng/mL. |
Molecular Mass : | 35-40 kDa |
Protein length : | Ser23-Met226 |
Endotoxin : | < 1.0 EU/μg of the protein by LAL method. |
Purity : | > 92% by SDS-PAGE. |
Storage : | Store the lyophilized protein at -20°C to -80 °C for long term. After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week. |
Reconstitution : | Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. |
Gene Name : | SLAMF7 SLAM family member 7 [ Homo sapiens ] |
Official Symbol : | SLAMF7 |
Synonyms : | SLAMF7; SLAM family member 7; 19A; CD319; CRACC; CS1; protein 19A; CD2 subset 1; 19A24 protein; membrane protein FOAP-12; CD2-like receptor activating cytotoxic cells; CD2-like receptor-activating cytotoxic cells; novel LY9 (lymphocyte antigen 9) like protein; |
Gene ID : | 57823 |
mRNA Refseq : | NM_021181 |
Protein Refseq : | NP_067004 |
MIM : | 606625 |
UniProt ID : | Q9NQ25 |
Products Types
◆ Recombinant Protein | ||
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Slamf7-5898M | Recombinant Mouse Slamf7 Protein, Myc/DDK-tagged | +Inquiry |
SLAMF7-187H | Recombinant Human SLAMF7 protein, His-Avi-tagged, Biotinylated | +Inquiry |
SLAMF7-1555C | Recombinant Cynomolgus SLAMF7 protein, His-tagged | +Inquiry |
◆ Lysates | ||
SLAMF7-2378HCL | Recombinant Human SLAMF7 cell lysate | +Inquiry |
SLAMF7-2591MCL | Recombinant Mouse SLAMF7 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewIt has a high solubility and can be easily prepared at the desired concentration.
It was found to be well active and could effectively perform the required biological activity experiments.
It was observed that SLAMF7 had good crystallinity, which was conducive to crystallography research.
Q&As (6)
Ask a questionSLAMF7 protein is involved in regulating immune cell activation, proliferation, and transmission of background signals by binding to activating ligands, such as CD319, thereby influencing the immune response.
By combining with immunotherapy, such as anti-PD-1 antibodies, the immune response can be further enhanced and the anti-tumor effect can be improved. The study of SLAMF7 protein provides a new direction for the development of combinatorial therapeutic strategies.
This protein is mainly expressed in the immune system, including immune cells such as plasma cells, NK cells, and activated T cells.
The role of SLAMF7 protein in other types of cancer is unclear, and further research is needed to determine its potential role in other cancers.
Yes, the SLAMF7 protein has been shown to be a potential therapeutic target. A monoclonal antibody drug targeting SLAMF7 protein (Elotuzumab) has been developed for the treatment of multiple myeloma.
SLAMF7 protein interacts with NK cells in multiple myeloma and plays a role in inhibiting and controlling tumor growth by activating the anti-tumor activity of NK cells.
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