Active Recombinant Human ST3GAL1 Protein (AA 52-340), N-6×His/GFP tagged

• Cat.No.: ST3GAL1-05H
• Product Overview: Recombinant Human ST3GAL1 Protein (AA 52-340) with N-6×His/GFP tag was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet.
• Source: HEK293
• Species: Human
• Tag: N-6×His, GFP
• Bio-activity: ≥0.95 μmol/min/mg
• Molecular Mass: ~70 kDa
• Protein Length: AA 52-340
• AA Sequence: RLIKHRPCTCTHCIGQRKLSAWFDE RFNQTMQPLLTAQNALLEDDTYRWW LRLQREKKPNNLNDTIKELFRVVPG NVDPMLEKRSVGCRRCAVVGNSGNL RESSYGPEIDSHDFVLRMNKAPTAG FEADVGTKTTHHLVYPESFRELGDN VSMILVPFKTIDLEWVVSAITTGTI SHTYIPVPAKIRVKQDKILIYHPAF IKYVFDNWLQGHGRYPSTGILSVIF SMHVCDEVDLYGFGADSKGNWHHYW ENNPSAGAFRKTGVHDADFESNVTA TLASINKIRIFKGR
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by Coomassie Blue stain.
• Stability: 6 months if stored at -80 centigrade. Avoid repeated freeze thaws.
• Concentration: 1 mg/mL
• Storage Buffer: Supplied as a 0.2 μm filtered solution in 20mM HEPES pH 7.0 and 100mM NaCl buffer, with 10% Glycerol.
• Preservative: 0.05 % NaN3
• Shipping: This product is shipped as 0.2μm filtered product on dry ice.

Gene Information

• Gene Name: ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [ Homo sapiens (human) ]
• Official Symbol: ST3GAL1
• Synonyms: ST3GAL1; ST3 beta-galactoside alpha-2,3-sialyltransferase 1; sialyltransferase 4A (beta galactosidase alpha 2,3 sialytransferase) , SIAT4A; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; SIATFL; ST3Gal I; ST3GalA.1; ST3O; SIAT4-A; ST3GalI; alpha 2,3-ST 1; beta-galactoside alpha-2,3-sialyltransferase 1; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; sialyltransferase 4A (beta-galactoside alpha-2,3-sialytransferase); sialyltransferase 4A (beta-galactoside alpha-2,3-sialyltransferase); sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase); SIAT4A; ST3GalA; ST3GalIA; Gal-NAc6S; ST3GalIA,1; MGC9183; FLJ36548; DKFZp666E036; DKFZp779K2051
• Gene ID: 6482
• mRNA Refseq: NM_003033
• Protein Refseq: NP_003024
• MIM: 607187
• UniProt ID: Q11201