Active Recombinant Human ST6GALNAC1 Protein (AA 36-600), N-6×His/GFP tagged

• Cat.No.: ST6GALNAC1-17H
• Product Overview: Recombinant Human ST6GALNAC1 Protein (AA 36-600) with N-6×His/GFP tag was expressed in HEK293.

Specification

• Description: Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).
• Source: HEK293
• Species: Human
• Tag: N-6×His, GFP
• Bio-activity: ≥0.1 μmol/min/mg
• Molecular Mass: ~90 kDa
• Protein Length: AA 36-600
• AA Sequence: MRSCLWRCRHLSQGVQWSLLLAVLV FFLFALPSFIKEPQTKPSRHQRTEN IKERSLQSLAKPKSQAPTRARRTTI YAEPVPENNALNTQTQPKAHTTGDR GKEANQAPPEEQDKVPHTAQRAAWK SPEKEKTMVNTLSPRGQDAGMASGR TEAQSWKSQDTKTTKGNGGQTRKLT ASRTVSEKHQGKAATTAKTLIPKSQ HRMLAPTGAVSTRTRQKGVTTAVIP PKEKKPQATPPPAPFQSPTTQRNQR LKAANFKSEPRWDFEEKYSFEIGGL QTTCPDSVKIKASKSLWLQKLFLPN LTLFLDSRHFNQSEWDRLEHFAPPF GFMELNYSLVQKVVTRFPPVPQQQL LLASLPAGSLRCITCAVVGNGGILN NSHIGQEIDSHDYVFRLSGALIKGY EQDVGTRTSFYGFTAFSLTQSLLIL GNRGFKNVPLGKAQTPGSFSGSPAH GQVPVAAPRLSPIHEEQVSEV
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by Coomassie Blue stain.
• Stability: 6 months if stored at -80 centigrade. Avoid repeated freeze thaws.
• Concentration: 1 mg/mL
• Storage Buffer: Supplied as a 0.2 μm filtered solution in 20mM HEPES pH 7.0 and 100mM NaCl buffer, with 10% Glycerol.
• Preservative: 0.05 % NaN3
• Shipping: This product is shipped as 0.2μm filtered product on dry ice.

Gene Information

• Gene Name: ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 [ Homo sapiens (human) ]
• Official Symbol: ST6GALNAC1
• Synonyms: ST6GALNAC1; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; sialyltransferase 7 ((alpha N acetylneuraminyl 2,3 beta galactosyl 1,3) N acetyl galactosaminide alpha 2,6 sialyltransferase) A , SIAT7A; alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6GalNAcI; SIAT7-A; ST6GalNAc I; sialyltransferase 7A; galNAc alpha-2,6-sialyltransferase I; GalNAc alpha-2, 6-sialyltransferase I, long form; sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) A; STYI; SIAT7A; HSY11339
• Gene ID: 55808
• mRNA Refseq: NM_018414
• Protein Refseq: AAH22462
• MIM: 610138
• UniProt ID: Q9NSC7