Active Recombinant Human TGFA protein
Cat.No. : | TGFa-149H |
Product Overview : | Recombinant Human TGFA protein(P01135-1)(Val40-Ala89) was expressed in E. coli. |
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Source : | E. coli |
Species : | Human |
Tag : | Non |
Form : | Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | 1.Measured by its binding ability in a functional ELISA. Immobilized Human TGF-alpha at 2 μg/ml (100 μl/well) can bind Human EGFR hFc, the EC50 of Human EGFR hFc is 80-500 ng/mL.2. Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.5-2.5 ng/mL. |
Molecular Mass : | The recombinant human TGFa consists of 50 amino acids and has a predicted molecular mass of 5.6 kDa. The apparent molecular mass of it is approximately 13 kDa in SDS-PAGE under reducing conditions. |
Protein length : | Val40-Ala89 |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | TGFA transforming growth factor, alpha [ Homo sapiens ] |
Official Symbol : | TGFA |
Synonyms : | TGFA; transforming growth factor, alpha; protransforming growth factor alpha; TGF-alpha; TFGA; |
Gene ID : | 7039 |
mRNA Refseq : | NM_001099691 |
Protein Refseq : | NP_001093161 |
MIM : | 190170 |
UniProt ID : | P01135 |
Products Types
◆ Recombinant Protein | ||
TGFA-2763H | Recombinant Human TGFA Protein, His-tagged | +Inquiry |
TGFA-9159M | Recombinant Mouse TGFA Protein, His (Fc)-Avi-tagged | +Inquiry |
TGFA-1538S | Recombinant Sheep TGFA Protein (24-97 aa), GST-tagged | +Inquiry |
TGFA-5692R | Recombinant Rat TGFA Protein, His (Fc)-Avi-tagged | +Inquiry |
TGFA-2127R | Recombinant Rabbit TGFA Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
TGFA-29704TH | Recombinant Human TGFA | +Inquiry |
◆ Lysates | ||
TGFA-1121HCL | Recombinant Human TGFA 293 Cell Lysate | +Inquiry |
Related Gene
Not For Human Consumption!
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Q&As (7)
Ask a questionIt stimulates cell proliferation and survival, playing a key role in tissue development.
Genetic mutations in TGFA can lead to impaired wound healing and tissue regeneration.
Altered TGFA activity is linked with cancer progression, as it can stimulate uncontrolled cell growth.
TGFA, a growth factor, is vital for activating signaling pathways that control cell growth and differentiation.
Targeting TGFA offers potential for treating wounds and cancer by modulating growth factor signaling.
TGFA interacts with epidermal growth factor receptors, influencing various cellular processes.
TGFA is important in wound healing, promoting the regeneration of skin and other tissues.
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