Active Recombinant Human TNFRSF17 Protein, Fc-tagged, FITC conjugated
Cat.No. : | TNFRSF17-121HF |
Product Overview : | The FITC conjugated extracellular domain of human BCMA (aa 2-54) is fused at the C-terminus to the Fc portion of human IgG1. |
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Description : | BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. Its downstream signaling is dependent on NF-kappa; B and JNK. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized |
Bio-activity : | Blocks the binding of BAFF and APRIL to their receptors BCMA and TACI, inhibiting BAFF- and APRIL-mediated B cell activation. |
Molecular Mass : | ~40 kDa (SDS-PAGE) |
Purity : | ≥95 % by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with FITC via amines Excitation source: 488 nm spectral line, argon-ion laser Excitation Wavelength: 488 nm Emission Wavelength: 535 nm |
Stability : | Stable for at least 6 months after receipt when stored at -20 centigrade. |
Storage : | Short Term Storage: +4 centigrade; Long Term Storage: -20 centigrade. After reconstitution, prepare aliquots and store at -20 centigrade. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
Concentration : | 1 mg/mL |
Storage Buffer : | Contains PBS. |
Gene Name : | TNFRSF17 tumor necrosis factor receptor superfamily, member 17 [ Homo sapiens ] |
Official Symbol : | TNFRSF17 |
Synonyms : | TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCMA; tumor necrosis factor receptor superfamily member 17; BCM; CD269; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein; |
Gene ID : | 608 |
mRNA Refseq : | NM_001192 |
Protein Refseq : | NP_001183 |
MIM : | 109545 |
UniProt ID : | Q02223 |
Products Types
◆ Lysates | ||
TNFRSF17-2593MCL | Recombinant Mouse TNFRSF17 cell lysate | +Inquiry |
TNFRSF17-1253CCL | Recombinant Cynomolgus TNFRSF17 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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