Active Recombinant Human TNFRSF18 protein, His-Avi-tagged, Biotinylated
Cat.No. : | TNFRSF18-2091H |
Product Overview : | Biotinylated Recombinant Human TNFRSF18 protein(Gln 26 - Glu 161), fused with His and Avi tag, was expressed in HEK293. |
Availability | February 10, 2025 |
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Source : | HEK293 |
Species : | Human |
Tag : | His&Avi |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant. |
Bio-activity : | Immobilized Human GITR Ligand Protein, Fc Tag at 10 μg/mL (100 μL/well) can bind Biotinylated Human GITR Protein, His,Avitag with a linear range of 0.2-8 ng/mL. |
Molecular Mass : | This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™)The protein has a calculated MW of 18.1 kDa. The protein migrates as 22-26 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Gln26-Glu161 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. >95% as determined by SEC-MALS. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please protect from light and avoid repeated freeze-thaw cycles.This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | TNFRSF18 tumor necrosis factor receptor superfamily, member 18 [ Homo sapiens ] |
Official Symbol : | TNFRSF18 |
Synonyms : | TNFRSF18; tumor necrosis factor receptor superfamily, member 18; tumor necrosis factor receptor superfamily member 18; AITR; CD357; GITR; activation-inducible TNFR family receptor; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein; GITR-D; |
Gene ID : | 8784 |
mRNA Refseq : | NM_004195 |
Protein Refseq : | NP_004186 |
MIM : | 603905 |
UniProt ID : | Q9Y5U5 |
Products Types
◆ Recombinant Protein | ||
TNFRSF18-662M | Recombinant Mouse TNFRSF18 Protein | +Inquiry |
Tnfrsf18-6754M | Recombinant Mouse Tnfrsf18 protein, His-tagged | +Inquiry |
TNFRSF18-2769H | Recombinant Human TNFRSF18 Protein, His-tagged | +Inquiry |
Tnfrsf18-2770M | Recombinant Mouse Tnfrsf18 Protein, His-tagged | +Inquiry |
TNFRSF18-663M | Recombinant Mouse TNFRSF18 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
TNFRSF18-1143HCL | Recombinant Human TNFRSF18 cell lysate | +Inquiry |
TNFRSF18-1245RCL | Recombinant Rat TNFRSF18 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewThis flexibility enables researchers like myself to tailor TNFRSF18 protein experiments to our unique needs, enhancing the reliability and relevance of the obtained results.
Their commitment to delivering exceptional products and assisting with any challenges that may arise ensures a successful and rewarding experimental journey.
The TNFRSF18 protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.
Q&As (5)
Ask a questionClinical trials are investigating TNFRSF18 agonists, such as monoclonal antibodies, in combination with other cancer treatments in various cancer types.
As of my knowledge cutoff date in January 2022, there were no approved TNFRSF18-targeted therapies for cancer. However, this may have changed since then.
Side effects may include immune-related adverse events, similar to those seen with other immunotherapies, and can range from mild to severe.
TNFRSF18-targeted therapies may enhance the body's immune response against cancer cells, leading to better tumor control and improved patient outcomes.
Yes, combination therapies involving TNFRSF18 agonists and other immunotherapies are under investigation to improve treatment efficacy.
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