Active Recombinant Human TNFRSF4 Protein, Fc-tagged, Alexa Fluor® 647 conjugated
Cat.No. : | TNFRSF4-20H |
Product Overview : | Recombinant human Alexa Fluor® 647 conjugated OX40 (Leu29-Ala216) protein with human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in mouse myeloma cell line. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
Source : | Mouse myeloma cell line |
Species : | Human |
Tag : | Fc |
Form : | Disulfide-linked homodimer Labeled with Alexa Fluor® 647 Excitation Wavelength: 650 nm Emission Wavelength: 668 nm |
Bio-activity : | Measured by flow cytometry for its ability to bind anti-Human OX40/TNFRSF4 Monoclonal Antibody conjugated beads. The concentration of Recombinant Human OX40/TNFRSF4 Fc Chimera Alexa Fluor® 647 that produces 50% of the binding response is 1.5-15 ng/mL. |
Molecular Mass : | 46.7 kDa |
N-terminal Sequence Analysis : | Leu29 |
Endotoxin : | <1.0 EU/μg of the protein by the LAL method. |
Purity : | >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Storage : | Protect from light. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after opening. 3 months, -20 to -70 centigrade under sterile conditions after opening. |
Storage Buffer : | Supplied as a 0.2 μm filtered solution in PBS with BSA as a carrier protein. |
Shipping : | The product is shipped with dry ice or equivalent. |
Gene Name : | TNFRSF4 TNF receptor superfamily member 4 [ Homo sapiens (human) ] |
Official Symbol : | TNFRSF4 |
Synonyms : | TNFRSF4; TNF receptor superfamily member 4; OX40; ACT35; CD134; IMD16; TXGP1L; tumor necrosis factor receptor superfamily member 4; ACT35 antigen; ATC35 antigen; CD134 antigen; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; lymphoid activation antigene ACT35; tax-transcriptionally activated glycoprotein 1 receptor |
Gene ID : | 7293 |
mRNA Refseq : | NM_003327 |
Protein Refseq : | NP_003318 |
MIM : | 600315 |
UniProt ID : | P43489 |
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◆ Lysates | ||
TNFRSF4-1762MCL | Recombinant Mouse TNFRSF4 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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