Active Recombinant Human TNFRSF6B protein, hFc-tagged

• Cat.No.: TNFRSF6B-432H
• Product Overview: Active Recombinant Human TNFRSF6B protein(O95407)(Met1-His300) was expressed in Insect Cells with the Fc region of human IgG1 at the C-terminus.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Fc
• Protein Length: 1-300 aa
• Form: Lyophilized from sterile 100mM Glycine, 10mM NaCl, pH 7.0.
• Bio-activity: Measured by its ability to inhibit Fas Ligand induced apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is typically 0.01-0.05 μg/mL in the presence of 20 ng/mL recombinant human Fas Ligand.
• Molecular Mass: The recombinant human DCR3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 508 amino acids and has a predicted molecular mass of 56.4 kDa. The apparent molecular mass of the protein is approximately 65 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1 EU/µg as determined by LAL test.
• Purity: > 85 % as determined by SDS-PAGE
• Storage: Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy [ Homo sapiens ]
• Official Symbol: TNFRSF6B
• Synonyms: TNFRSF6B; tumor necrosis factor receptor superfamily, member 6b, decoy; tumor necrosis factor receptor superfamily member 6B; DcR3; DCR3; M68; TR6; decoy receptor 3; decoy receptor for Fas ligand; M68E; DJ583P15.1.1
• Gene ID: 8771
• mRNA Refseq: NM_003823
• Protein Refseq: NP_003814
• MIM: 603361
• UniProt ID: O95407