| Species : |
Human |
| Source : |
Insect Cells |
| Tag : |
Fc |
| Protein Length : |
Met1-His300 |
| similar : |
TNFRSF6B |
| Alias : |
TNFRSF6B; tumor necrosis factor receptor superfamily, member 6b, decoy; tumor necrosis factor receptor superfamily member 6B; DcR3; DCR3; M68; TR6; decoy receptor 3; decoy receptor for Fas ligand; M68E; DJ583P15.1.1; |
| Conjugate : |
C-hFc |
| Form : |
Lyophilized from sterile 100mM Glycine, 10mM NaCl, pH 7.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
| Bioactivity : |
Measured by its ability to inhibit Fas Ligand induced apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is typically 0.5-3 μg/mL in the presence of 200 ng/mL recombinant human Fas ligand. |
| MolecularMass : |
The recombinant human DCR3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 508 amino acids and has a predicted molecular mass of 56.4 kDa. The apparent molecular mass of the protein is approximately 65 kDa in SDS-PAGE under reducing conditions. |
| Endotoxin : |
< 1.0 EU per μg of the protein as determined by the LAL method |
| Purity : |
> 85 % as determined by SDS-PAGE |
| Storage : |
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Reconstitution : |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
| GeneName : |
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy [ Homo sapiens ] |
| GeneNameWeblink : |
8771 |
| OfficialSymbol : |
TNFRSF6B |
| OfficialSymbolWeblink : |
8771 |
| GeneID : |
8771 |
| GeneIDWeblink : |
8771 |
| mRNARefseq : |
NM_003823 |
| mRNARefseqWeblink : |
NM_003823.3 |
| ProteinRefseqWeblink : |
NP_003814.1 |
| MIMWeblink : |
603361 |
| UniProtID : |
O95407 |
| UniProtIDWeblink : |
O95407 |
