Active Recombinant Mouse CD200, MIgG2a Fc-tagged, mutant
Cat.No. : | CD200-002M |
Product Overview : | The extracellular domain of mouse CD200 (NP_034948.3)(Gln31-Ser236) is fused to the N-terminus of the Fc portion of a mutant mouse IgG2a was expressed in CHO cell. |
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Description : | The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, andthus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that thisgene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diversetissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found forthis gene |
Source : | CHO cells |
Species : | Mouse |
Tag : | MIgG2a Fc-tagged, mutant |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its binding ability in a functional ELISA. |
Molecular Mass : | 52 KDa |
AA Sequence : | Gln31-Ser236 |
Endotoxin : | <0.06 eu/μg as determined by lal>0.06> |
Purity : | ≥98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Protein length : | Gln31-Ser236 |
Gene Name : | Cd200 CD200 antigen [ Mus musculus ] |
Official Symbol : | CD200 |
Synonyms : | CD200; CD200 antigen; OX-2 membrane glycoprotein; MRC OX-2 antigen; antigen identified by monoclonal MRC OX-2; OX2; Mox2; |
Gene ID : | 17470 |
mRNA Refseq : | NM_010818 |
Protein Refseq : | NP_034948 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; |
Function : | protein binding; |
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◆ Lysates | ||
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Not For Human Consumption!
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Write a reviewSwift protein sequencing, helps identify unknown proteins.
Great protein crystallization services, key for structural biology.
Invaluable protein-protein interaction assays, integral for research.
Q&As (7)
Ask a questionCD200 regulates bone marrow and hematopoietic environments, supporting stem cell maintenance and differentiation.
CD200 contributes to immune evasion in cancers, affecting tumor progression and response to immunotherapy.
CD200 plays a role in suppressing inflammatory responses, which is crucial in autoimmune disease management.
Dysregulation of CD200 affects tissue graft rejection, influencing transplant tolerance and success.
Changes in CD200 expression impact the aging immune system, affecting age-related immune regulation and function.
CD200 expression influences neuroinflammatory processes, potentially impacting neurodegenerative diseases.
CD200 interacts with CD200R to modulate immune responses, promoting immune tolerance and reducing inflammation.
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