Active Recombinant Mouse CD3E & CD3G protein, His-Avi&Flag-tagged, Biotinylated
Cat.No. : | CD3E & CD3G-3036M |
Product Overview : | Biotinylated Recombinant Mouse CD3E&CD3G protein(Asp 23-Asp 108 (CD3E) & Gln 23-Ser 116 (CD3G)), fused with His-Avi and Flag tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Mouse |
Tag : | His-Avi&Flag |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. |
Bio-activity : | Immobilized CD3E Monoclonal Antibody (145-2C11) at 1 μg/mL (100 μL/well) can bind Biotinylated Mouse CD3E&CD3G Heterodimer Protein, His,Avitag&Flag Tag with a linear range of 5-78 ng/mL. |
Molecular Mass : | Biotinylated Mouse CD3E&CD3G Heterodimer Protein, His,Avitag&Flag Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 16.8 kDa (CD3E) and 15.2 kDa (CD3G). Subunit CD3E carries a polyhistidine tag at the C-terminus, followed by an Avi tag and subunit CD3G is fused with a flag tag at the C-terminus. As a result of glycosylation, the protein migrates as 20-23 kDa under reducing (R) condition, and 35-40 kDa under non-reducing (NR) condition (SDS-PAGE). |
Protein Length : | Asp 23-Asp 108 (CD3E) & Gln 23-Ser 116 (CD3G) |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE.>90% as determined by SEC-MALS. |
Storage : | For long term storage, the product should be stored at lyophilized state at-20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after storage at:-20°C to-70°C for 12 months in lyophilized state;-70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Cd3e CD3 antigen, epsilon polypeptide [ Mus musculus ] |
Official Symbol : | CD3E |
Synonyms : | CD3E; CD3 antigen, epsilon polypeptide; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3; T3e; AI504783; CD3epsilon; |
Gene ID : | 12501 |
mRNA Refseq : | NM_007648 |
Protein Refseq : | NP_031674 |
Products Types
◆ Recombinant Protein | ||
CD3E-138H | Recombinant Human CD3E Protein, His-tagged, Biotinylated | +Inquiry |
CD3E-141H | Recombinant Human CD3E Protein, His-tagged | +Inquiry |
CD3E-0803H | Recombinant Human CD3E Protein, GST-Tagged | +Inquiry |
Cd3e-674M | Recombinant Mouse Cd3e Protein, His&GST-tagged | +Inquiry |
CD3E-30H | Recombinant Human CD3E Protein (198 AA), C-Fc-tagged | +Inquiry |
◆ Lysates | ||
CD3E-1602CCL | Recombinant Cynomolgus CD3E cell lysate | +Inquiry |
CD3E-1275HCL | Recombinant Human CD3E cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, CD3E levels and T-cell function can be monitored to evaluate the response to cancer immunotherapies like checkpoint inhibitors.
There are currently no approved therapies that directly target CD3E, but it is a target for research in developing immunotherapies and cancer treatments.
There may be ongoing clinical trials using CD3E-targeted therapies in the context of cancer and autoimmune diseases. It's important to check clinical trial databases for specific studies.
Yes, monitoring CD3E levels in HIV-infected individuals can provide valuable information about the progression of the disease and the effectiveness of antiretroviral therapy.
CD3E can be used in research to study T-cell responses in allergic conditions, helping to better understand and diagnose allergies.
Customer Reviews (3)
Write a reviewManufacturers with the capacity for bulk production can offer CD3E protein in larger quantities, which is advantageous for researchers working on large-scale experiments or collaborations.
bulk production often leads to economies of scale, making the CD3E protein more cost-effective for research budgets.
Manufacturers can actively seek collaborations and partnerships with researchers to develop new applications or optimize methodologies using CD3E protein.
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