Active Recombinant Mouse Chemokine (C-C motif) Ligand 2 Ccl2-282M

Active Recombinant Mouse Chemokine (C-C motif) Ligand 2

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Active Recombinant Mouse Chemokine (C-C motif) Ligand 2

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Cat.No. : Ccl2-282M Optional Service: Optional requirements on this protein
Product Overview : Recombinant Murine JE(MCP-1) produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 125 amino acids and having a molecular mass of 13803 Dalton.
Description : Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1) and small inducible cytokine A2. CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury, infection, and inflammation.
Species : Mouse
Source : E.coli
Form : Lyophilized with no additives.
Purity : Purity Greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Bio-activity : Murine JE(MCP-1)is fully biologically active when compared to standard. The Biological activity is calculated by its ability to chemoattract Balb/C mouse spleen MNCs at 1.0-20.0 ng/ml.
Physical Appearance : Sterile Filtered white lyophilized (freeze-dried) powder.
Solubility : It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mgμs/ml, which can be further diluted into other aqueous solutions.
Purity Greater than 98% as determined by : Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Protein Content determined by : UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Amino acid sequence : QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEW-V QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVK-LTRKS EANASTTFST TTSSTSVGVT SVTVN
Storage : Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
Pathways : Chemokine signaling pathway; Cytokine-cytokine receptor interaction
PDB rendering based on 1dok. :

Gene Name : Ccl2 chemokine (C-C motif) ligand 2 [ Mus musculus ]
Official Symbol : Ccl2
Synonyms : Ccl2; chemokine (C-C motif) ligand 2; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594; monocyte chemoattractant protein-1; monocyte chemotactic protein; OTTMUSP00000000786; small inducible cytokine A2; monocyte chemotactic protein
Gene ID : 20296
mRNA Refseq : NM_011333
Protein Refseq : NP_035463
UniProt ID : P10148
Chromosome Location : 11 C-E1; 11 46.5 cM
Function : G-protein-coupled receptor binding; chemokine activity; cytokine activity; protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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