Active Recombinant Mouse Chemokine (C-C motif) Ligand 2
Cat.No. : | Ccl2-282M |
Product Overview : | Recombinant Murine JE(MCP-1) produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 125 amino acids and having a molecular mass of 13803 Dalton. |
- Specification
- Gene Information
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Cat. No. : | Ccl2-282M |
Description : | Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1) and small inducible cytokine A2. CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury, infection, and inflammation. |
Species : | Mouse |
Source : | E.coli |
Form : | Lyophilized with no additives. |
Purity : | Purity Greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE. |
Bio-activity : | Murine JE(MCP-1)is fully biologically active when compared to standard. The Biological activity is calculated by its ability to chemoattract Balb/C mouse spleen MNCs at 1.0-20.0 ng/ml. |
Physical Appearance : | Sterile Filtered white lyophilized (freeze-dried) powder. |
Solubility : | It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mgμs/ml, which can be further diluted into other aqueous solutions. |
Purity Greater than 98% as determined by : | Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE. |
Protein Content determined by : | UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard. |
Amino acid sequence : | QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEW-V QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVK-LTRKS EANASTTFST TTSSTSVGVT SVTVN |
Storage : | Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage. |
Pathways : | Chemokine signaling pathway; Cytokine-cytokine receptor interaction |
Gene Name : | Ccl2 chemokine (C-C motif) ligand 2 [ Mus musculus ] |
Official Symbol : | Ccl2 |
Synonyms : | Ccl2; chemokine (C-C motif) ligand 2; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594; monocyte chemoattractant protein-1; monocyte chemotactic protein; OTTMUSP00000000786; small inducible cytokine A2; monocyte chemotactic protein |
Gene ID : | 20296 |
mRNA Refseq : | NM_011333 |
Protein Refseq : | NP_035463 |
UniProt ID : | P10148 |
Chromosome Location : | 11 C-E1; 11 46.5 cM |
Function : | G-protein-coupled receptor binding; chemokine activity; cytokine activity; protein binding |
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◆ Recombinant Protein | ||
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Ccl2-2030M | Active Recombinant Mouse Ccl2 Protein | +Inquiry |
◆ Lysates | ||
CCL2-001MCL | Recombinant Mouse CCL2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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