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Active Recombinant Mouse Chemokine (C-C motif) Ligand 2
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Cat.No. : | Ccl2-282M Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Murine JE(MCP-1) produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 125 amino acids and having a molecular mass of 13803 Dalton. |
Description : | Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1) and small inducible cytokine A2. CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury, infection, and inflammation. |
Species : | Mouse |
Source : | E.coli |
Form : | Lyophilized with no additives. |
Purity : | Purity Greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE. |
Bio-activity : | Murine JE(MCP-1)is fully biologically active when compared to standard. The Biological activity is calculated by its ability to chemoattract Balb/C mouse spleen MNCs at 1.0-20.0 ng/ml. |
Physical Appearance : | Sterile Filtered white lyophilized (freeze-dried) powder. |
Solubility : | It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mgμs/ml, which can be further diluted into other aqueous solutions. |
Purity Greater than 98% as determined by : | Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE. |
Protein Content determined by : | UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard. |
Amino acid sequence : | QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEW-V QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVK-LTRKS EANASTTFST TTSSTSVGVT SVTVN |
Storage : | Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage. |
Pathways : | Chemokine signaling pathway; Cytokine-cytokine receptor interaction |
PDB rendering based on 1dok. : |
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Gene Name : | Ccl2 chemokine (C-C motif) ligand 2 [ Mus musculus ] |
Official Symbol : | Ccl2 |
Synonyms : | Ccl2; chemokine (C-C motif) ligand 2; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594; monocyte chemoattractant protein-1; monocyte chemotactic protein; OTTMUSP00000000786; small inducible cytokine A2; monocyte chemotactic protein |
Gene ID : | 20296 |
mRNA Refseq : | NM_011333 |
Protein Refseq : | NP_035463 |
UniProt ID : | P10148 |
Chromosome Location : | 11 C-E1; 11 46.5 cM |
Function : | G-protein-coupled receptor binding; chemokine activity; cytokine activity; protein binding |
◆ Recombinant Protein
CCL2-0622H | Recombinant Human CCL2 Protein, GST-Tagged | +Inquiry |
CCL2-11H | Recombinant Human CCL2 Protein, His-tagged | +Inquiry |
CCL2-337C | Recombinant Human CCL2 Protein (76 aa) | +Inquiry |
CCL2-2145R | Recombinant Rhesus monkey CCL2 Protein, His-tagged | +Inquiry |
Ccl2-2030M | Recombinant Mouse Ccl2 Protein | +Inquiry |
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◆ Lysates
CCL2-001MCL | Recombinant Mouse CCL2 cell lysate | +Inquiry |
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CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b
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