Active Recombinant Mouse Ctla4, MIgG2a Fc-tagged
Cat.No. : | Ctla4-4556M |
Product Overview : | The extracellular domain of mouse CD152[CTLA-4](NP_033973.2) (ILe38-Ser160) is fused to the N-terminus of the Fc portion of mouse IgG2a, was expressed in NS1 cell. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the immunoglobulin superfamily, and encodes a protein that functions as a negative regulator of T-cell responses. Alternatively spliced transcript variants encoding different isoforms have been described for this gene |
Source : | NS1 cells |
Species : | Mouse |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Binds both CD80 (B7-1) and CD86 (B7-2) with high affinity and inhibits CD28 signaling competitively. Kills the target cell completely. |
Molecular Mass : | 44 KDa |
AA Sequence : | ILe38-Ser160 |
Endotoxin : | <0.06 EU/μg as determined by LAL test. |
Purity : | ≥98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | Ctla4 cytotoxic T-lymphocyte-associated protein 4 [ Mus musculus ] |
Official Symbol : | Ctla4 |
Synonyms : | CTLA4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte protein 4; CD152 antigen; cytotoxic T-lymphocyte-associated antigen 4; Cd152; Ly-56; Ctla-4; |
Gene ID : | 12477 |
mRNA Refseq : | NM_009843 |
Protein Refseq : | NP_033973 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CTLA4 inhibitory signaling, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; |
Products Types
◆ Recombinant Protein | ||
CTLA4-1106H | Recombinant Human CTLA4 Protein (Met1-Phe162), HlgG1 Fc-tagged, Biotinylated | +Inquiry |
CTLA4-499H | Recombinant Human CTLA4 Protein (Met1-Phe162), HIgG1 Fc-tagged | +Inquiry |
CTLA4-4413B | Recombinant Bovine CTLA4 Protein | +Inquiry |
Ctla4-158M | Recombinant Mouse Ctla4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ctla4-038M | Active Recombinant Mouse Ctla4 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
CTLA4-2526HCL | Recombinant Human CTLA4 cell lysate | +Inquiry |
CTLA4-2179MCL | Recombinant Mouse CTLA4 cell lysate | +Inquiry |
CTLA4-1047CCL | Recombinant Cynomolgus CTLA4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1712 | CTLA4:B7-1[Biotinylated] Inhibitor Screening Assay Kit | +Inquiry |
Kit-1713 | CTLA4[Biotinylated]:B7-2 Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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