Active Recombinant Mouse Dentin Matrix Protein 1, His-tagged

• Cat.No.: Dmp1-407M
• Product Overview: Recombinantmouse Dmp1 protein was expressed in Murine myeloma cell line, NS0-derived, with a C-terminal6-His tag.Leu17-Tyr503.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: His
• Protein Length: 17-503 a.a.
• Description: Dmp1 is a member ofthe SIBLING family of proteins that includes bone sialoprotein, dentinsialophosphoprotein, MEPE, and osteopontin. These are highly phosphorylated integrinbindingproteins that are rich in acidic amino acids.
• Form: Lyophilized from a0.2 μm filtered solution in PBS.
• N-terminal Sequence: Leu17
• Molecular Weight: 52.9 kDa
• Activity: Measured by itsbinding ability in a functional ELISA. Immobilized rhIntegrin αVß3 at 5 μg/mLcan bind rmDMP-1 with an apparent KD < 25 nM.
• Endotoxin Level: <1.0 EU per 1 μgof the protein by the LAL method.
• Purity: >85%,by SDS-PAGE under reducing conditions and visualized by silver stain.
• Reconstitution: Reconstitute at 100μg/mL in sterile PBS.
• Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month,2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions afterreconstitution.

Gene Information

• Gene Name: Dmp1dentin matrix protein 1 [ Mus musculus ]
• Official Symbol: Dmp1
• Synonyms: Dmp1; dentinmatrix protein 1; PP; Dmp; AV020965; dentinmatrix acidic phospoprotein 1; AG1; DMP-1; serine rich acidic phospoprotein
• Gene ID: 13406
• mRNA Refseq: NM_016779
• Protein Refseq: NP_058059
• UniProt ID: O5518
• Chromosome Location: 5
• Function: extracellularmatrix binding