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Active Recombinant Mouse Fibroblast Growth Factor 1

Cat.No. : Fgf1-565M
Product Overview : M-FGF-acidic is non-glycosylated heparin binding protein comprised of 141 amino acid residues with a molecular weight of 15.9 kDa.
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Cat. No. : Fgf1-565M
Description : Recombinant Mouse Fibroblast Growth Factor-acidic is one of over 20 members of the FGF family. The fibroblast growth factors play a central role in prenatal development and growth and regeneration of cells during the proliferation and differentiation stages.
Species : Mouse
Source : E.coli
Form : Lyophilized at a concentration of 1 mg/ml in 5 mM NaP, 7.5 + 50 mM NaCl.
Purity : Purity Greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Bio-activity : Recombinant Human FGF-alpha is fully biologically active when compared to standards. The ED50, calculated by the dose-dependent proliferation of mouse BALB/c 3T3 cells, is less than 0.04ng/ml.
Physical Appearance : Sterile Filtered white lyophilized (freeze-dried) powder.
Solubility : Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 - 0.5 mg"s/ml, which can be further diluted into other aqueous solutions.
Purity Greater than 98% as determined by : Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Protein Content determined by : UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Endotoxin Level : Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Amino acid sequence : MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDTEGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
Storage : Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
Gene Name : Fgf1 fibroblast growth factor 1 [ Mus musculus ]
Official Symbol : Fgf1
Synonyms : Dffrx; Fam; Fgf-1; Fgfa; HBGF-1; ECGF-beta; FIBP; FGFIBP; FIBP-1; ECGF; ECGFA; GLIO703; FGF1; FGF-a; Heparin-binding growth factor 1; Acidic fibroblast growth factor; aFGF; ECGFB; FGF-alpha; FGFA; HBGF1; AFGF; Beta-endothelial cell growth factor; Heparin binding growth factor 1 precursor; endothelial cell growth factor alpha; endothelial cell growth factor beta; fibroblast growth factor 1 (acidic); heparin binding growth factor 1; Fgf1; fibroblast growth factor 1Dffrx; Fam; Fgf-1; Fgfa; HBGF-1; ECGF-beta; FIBP; FGFIBP; FIBP-1; ECGF; ECGFA; GLIO703; FGF1; FGF-a; Heparin-binding growth factor 1; Acidic fibroblast growth factor; aFGF; ECGFB; FGF-alpha; FGFA; HBGF1; AFGF; Beta-endothelial cell growth factor; Heparin binding growth factor 1 precursor; endothelial cell growth factor alpha; endothelial cell growth factor beta; fibroblast growth factor 1 (acidic); heparin binding growth factor 1
Gene ID : 14164
mRNA Refseq : NM_010197
Protein Refseq : NP_034327
UniProt ID : P61148
Chromosome Location : 18 19.0 cM
Pathway : MAPK signaling pathway; Melanoma; Regulation of actin cytoskeleton
Function : growth factor activity; heparin binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any clinical trials using FGF1 for heart disease? 06/28/2020

Yes, there have been clinical trials exploring the use of FGF1 in treating heart disease, specifically in promoting cardiac angiogenesis.

Can FGF1 be used in regenerative medicine? 09/15/2018

Yes, FGF1 is being investigated for its potential in regenerative medicine to repair damaged tissues and organs.

Can FGF1 be used in the treatment of diabetes? 03/29/2018

FGF1 has shown potential in improving insulin sensitivity and glucose regulation in preclinical studies, but further research is needed for clinical applications.

What safety concerns are associated with FGF1 use? 01/15/2017

Safety concerns include the risk of uncontrolled cell growth, which could lead to cancer, and the need for precise dosing and administration.

Are there any side effects associated with FGF1 therapy? 12/10/2016

Potential side effects may include inflammation at the application site, allergic reactions, and adverse effects related to uncontrolled cell growth.

Customer Reviews (3)

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Reviews
08/06/2021

    By using FGF1 protein, I can explore the mechanisms underlying cell division, cell cycle control, and the molecular pathways associated with these processes.

    06/03/2021

      The protein's interaction with other APC/C subunits enables the study of its function and the investigation of its involvement in various cellular processes.

      11/25/2018

        As a researcher utilizing FGF1 protein in my trials, I can highlight its advantages and the valuable support provided by the manufacturer in facilitating my research.

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