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Active Recombinant Mouse Flt1 Protein, Fc-tagged

Cat.No. : Flt1-1785M
Product Overview : Recombinant mouse Flt1 protein (Ser27-Glu759) with mouse IgG2A (Glu98-Lys330) tag at C-terminus was expressed in Mouse myeloma cell line.
  • Specification
  • Gene Information
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Description : Biased expression in placenta adult (RPKM 35.7), lung adult (RPKM 11.8) and 11 other tissues.
Source : Mammalian cells
Species : Mouse
Tag : Fc
Form : Lyophilized
Bio-activity : Measured by its ability to inhibit the VEGF-dependent proliferation of HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 5-30 ng/mL.
Molecular Mass : 109.6 kDa (monomer)
Endotoxin : <0.10 EU per 1 µg of the protein by the LAL method.
Purity : > 95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Storage Buffer : Lyophilized from a 0.2 µm filtered solution in PBS.
Reconstitution : Reconstitute at 100 µg/mL in PBS.
Shipping : The product is shipped at ambient temperature.
Publication :
Syndecan-1 and glycosaminoglycans in pre-eclamptic and normotensive pregnancies. (2017)
Soluble syndecan-1 and glycosaminoglycans in preeclamptic and normotensive pregnancies (2021)
Vascular damage and dysfunction in hypertensive emergencies (2017)
SFlt-1 Elevates Blood Pressure by Augmenting Endothelin-1-Mediated Vasoconstriction in Mice (2014)
Gene Name : Flt1 FMS-like tyrosine kinase 1 [ Mus musculus (house mouse) ]
Official Symbol : Flt1
Synonyms : Flt1; FMS-like tyrosine kinase 1; Flt-1; sFlt1; VEGFR1; VEGFR-1; AI323757; vascular endothelial growth factor receptor 1; embryonic receptor kinase 2; tyrosine-protein kinase receptor FLT; vascular permeability factor receptor; EC
Gene ID : 14254
mRNA Refseq : NM_010228
Protein Refseq : NP_034358
UniProt ID : P35969

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.



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