Active Recombinant Mouse GP1BA Protein, C-His-tagged
Cat.No. : | GP1BA-21M |
Product Overview : | Recombinant Mouse GP1BA Protein, fused to His-tag at C-terminus, was expressed in CHO. |
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Description : | Acts upstream of or within blood coagulation and cell morphogenesis. Colocalizes with anchored component of external side of plasma membrane. Is expressed in dorsal root ganglion; embryo; liver; and spinal cord. Used to study Bernard-Soulier syndrome. Human ortholog(s) of this gene implicated in Bernard-Soulier syndrome; Bernard-Soulier syndrome type A2; myocardial infarction; non-arteritic anterior ischemic optic neuropathy; and platelet-type bleeding disorder 3. Orthologous to human GP1BA (glycoprotein Ib platelet subunit alpha). |
Source : | CHO |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Bio-activity : | Measured by its binding ability in a functional ELISA. Recombinant Mouse CD42b/GPIb alpha is immobilized at 0.5 μg/mL (100 μL/well), the concentration of Recombinant Human vWF‑A2 that produces 50% optimal binding response is approximately 0.1-0.5μg/mL in the presence of ristocetin. |
Molecular Mass : | Predicted Molecular Mass: 66 kDa SDS-PAGE: 108-150 kDa, reducing conditions |
Protein Length : | Gln17-Pro612 |
N-terminal Sequence Analysis : | No results obtained: Gln17 inferred from enzymatic pyroglutamate treatment revealing His18 |
Endotoxin : | <0.10 EU per 1 μg of the protein by the LAL method. |
Purity : | >95%, by SDS-PAGE with silver staining |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | Reconstitute at 500 μg/mL in sterile PBS. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Related Research Areas : | Coagulation Myeloid Lineage Markers Platelet Adhesion Molecules Platelet Markers |
Gene Name : | Gp1ba glycoprotein 1b, alpha polypeptide [ Mus musculus (house mouse) ] |
Official Symbol : | GP1BA |
Synonyms : | GPIba; GPIbalpha; GP-Ib alpha |
Gene ID : | 14723 |
mRNA Refseq : | NM_010326.3 |
Protein Refseq : | NP_034456.2 |
UniProt ID : | O35930 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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