Active Recombinant Mouse Icosl, Fc-tagged, mutant

• Cat.No.: Icosl-356M
• Product Overview: The extracellular domain of mouse CD275 [B7-H2] (NP_056605.1)(Thr 48-Lys279) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a.

Specification

• Species: Mouse
• Source: CHO
• Tag: Fc
• Protein Length: 48-279 a.a.
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA. Immobilized human ICOS at 1 μg/ml (100μl/well) can bind biotinylated B7-H2(mouse):Fc (mouse) (rec.) (non-lytic) with a linear range of 0.1 - 1.0 μg/ml. Optimal dilutions should be determined by each l
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="">
• Purity: ≥98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Icosl
• Official Symbol: Icosl
• Synonyms: B7h; GI50; GL50; B7-H2; LICOS; B7RP-1; GL50-B; ICOS-L; Icoslg; Ly115l; AU044799; BG071784; mKIAA0653
• Gene ID: 50723
• mRNA Refseq: NM_015790
• Protein Refseq: NP_056605
• UniProt ID: Q9JHJ8
• Chromosome Location: 10 C1; 10
• Pathway: Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem
• Function: protein binding, receptor binding