Active Recombinant Mouse Il10 Protein (Ser19-Ser178), C-His tagged, Animal-free, Carrier-free
Cat.No. : | Il10-45M |
Product Overview : | Recombinant Mouse Il10 Protein (Ser19-Ser178) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. Many different types of cells can produce IL-10, including immune cells and non-immune cells. IL-10 exerts inhibitory functions on DCs and macrophages, which is a potent inhibitor of antigen presentation and limit the production of the Th1-associated cytokines IL-2 and interferon-γ (IFN-γ). IL-10 is also a key immunoregulator during infection due to its inhibitory effect on inflammatory cytokine production. Consequently, the excessive Th1 and CD8+ T cell responses could be suppressed during infection. |
Source : | E. coli |
Species : | Mouse |
Tag : | C-His |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to induce MC/9‑2 cells proliferation. The ED50 for this effect is < 1 ng/mL. The specific activity of recombinant mouse IL-10 is > 1 × 10⁶ IU/mg. |
Molecular Mass : | The protein has a calculated MW of 19.7 kDa. The protein migrates as 19 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Ser19-Ser178 |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >98% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | Il10 interleukin 10 [ Mus musculus (house mouse) ] |
Official Symbol : | Il10 |
Synonyms : | IL10; interleukin 10; interleukin-10; cytokine synthesis inhibitory factor; CSIF; Il-10; |
Gene ID : | 16153 |
mRNA Refseq : | NM_010548 |
Protein Refseq : | NP_034678 |
UniProt ID : | P18893 |
Products Types
◆ Recombinant Protein | ||
Il10-135M | Recombinant Active Mouse IL10 Protein, His-tagged(C-ter) | +Inquiry |
Il10-082M | Active Recombinant Mouse Il10 Protein | +Inquiry |
Il10-084M | Recombinant Mouse Il10 Protein, MYC/DDK-tagged | +Inquiry |
IL10-999C | Recombinant Chicken IL10 Protein, His&GST-tagged | +Inquiry |
IL10-2697H | Recombinant Human IL10 protein(19-178 aa), N-MBP & C-His-tagged | +Inquiry |
◆ Lysates | ||
IL10-2079HCL | Recombinant Human IL10 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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