Active Recombinant Mouse IL11 Protein
| Cat.No. : | IL11-131M |
| Product Overview : | Recombinant Mouse IL11 Protein without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling. |
| Source : | E. coli |
| Species : | Mouse |
| Bio-activity : | B9 cell proliferation, ED50≤250 ng/mL |
| Molecular Mass : | Monomer, 19.3 kDa (179 aa) |
| AA Sequence : | MPGPPAGSPRVSSDPRADLDSAVLL TRSLLADTRQLAAQMRDKFPADGDH SLDSLPTLAMSAGTLGSLQLPGVLT RLRVDLMSYLRHVQWLRRAGGPSLK TLEPELGALQARLERLLRRLQLLMS RLALPQAAPDQPVIPLGPPASAWGS IRAAHAILGGLHLTLDWAVRGLLLL KTRL |
| Endotoxin : | ≤1 EUs/μg, Kinetic LAL |
| Purity : | ≥95%, Reducing and Non-Reducing SDS PAGE |
| Stability : | 12 months from date of receipt when stored at -20 to -80 centigrade as supplied. 1 month when stored at 4 centigrade after reconstituting as directed. 3 months when stored at -20 to -80 centigrade after reconstituting as directed. |
| Storage : | Storage Prior to Reconstitution: -20 centigrade |
| Storage Buffer : | Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA) |
| Reconstitution : | Sterile water at 0.1 mg/mL |
| Shipping : | Room temperature |
| Instructions : | Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws. |
| Gene Name : | Il11 interleukin 11 [ Mus musculus (house mouse) ] |
| Official Symbol : | IL11 |
| Synonyms : | IL11; interleukin 11; interleukin-11; IL-11; |
| Gene ID : | 16156 |
| mRNA Refseq : | NM_008350 |
| Protein Refseq : | NP_032376 |
| UniProt ID : | P47873 |
Products Types
| ◆ Recombinant Protein | ||
| IL11-061H | Active Recombinant Human IL11 Protein | +Inquiry |
| Il11-1659R | Recombinant Rat Il11 Protein, His-tagged | +Inquiry |
| Il11-085M | Active Recombinant Mouse Il11 Protein | +Inquiry |
| IL11-130H | Active Recombinant Human IL11 Protein | +Inquiry |
| IL11-2289H | Recombinant Human IL11 Protein, His-tagged | +Inquiry |
| ◆ Lysates | ||
| IL11-5249HCL | Recombinant Human IL11 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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- Reviews
Q&As (10)
Ask a questionTransgenic mice and knockdown models explore IL11's impact on tissue regeneration.
Site-directed mutagenesis identifies key residues in IL11's interaction with IL11RA.
Chromatin immunoprecipitation and DNA methylation analysis decipher IL11's regulatory mechanisms.
Proteomics identifies IL11-interacting proteins and potential cross-talk partners.
Cell-based and luciferase reporter assays elucidate IL11's JAK-STAT signaling activation.
RNA sequencing uncovers IL11-induced gene expression changes across different cell types.
X-ray crystallography and NMR spectroscopy reveal structural details of the IL11-IL11RA complex.
Confocal and super-resolution microscopy visualize IL11 localization in tissues.
Techniques like surface plasmon resonance measure IL11-IL11RA binding affinity and kinetics.
CRISPR screening unveils genes and pathways influenced by IL11 signaling.
Customer Reviews (3)
Write a reviewPotent in bone regeneration models. -
Suitable for cell culture. -
High yield in expression. -
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