Active Recombinant Mouse Interleukin 17F
| Cat.No. : | Il17f-497M |
| Product Overview : | Recombinant Mouse IL-17F produced in E.coli is a homodimeric, non-glycosylated polypeptide chain containing a total of 133 amino acids and having a molecular mass of 14.9 kDa. |
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| Species : | Mouse |
| Source : | E.coli |
| Tag : | Non |
| Description : | Interleukin-17 (IL-17 or IL-17A) is the founding member of a group of cytokines called the IL-17 family. Interleukin 17 is a cytokine that acts as a potent mediator in delayed ?C type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation, similar to Interferon gamma. IL- 17 is produced by T helper cells and is induced by IL ?C 23 which results in destructive tissue damage in delayed ?C type reactions. |
| Form : | Lyophilized with no additives. |
| Purity : | Purity Greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE. |
| Bio-activity : | IL-17F is fully bioactive when compared to standard. The ED50 as determined by the dose-dependant induction of IL-6 in NHDF is 1.94 ng/ml. |
| Physical Appearance : | Sterile Filtered white lyophilized (freeze-dried) powder. |
| Solubility : | It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions. |
| Purity Greater than 98% as determined by : | Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE. |
| Protein Content determined by : | UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard. |
| Endotoxin Level : | Endotoxin level is <0.01ng/ug or <0.1EU/ug. |
| Amino acid sequence : | MRKNPKAGVP ALQKAGNCPP LEDNTVRVDI RIFNQNQGIS VPREFQNRSS SPWDYNITRD PHRFPSEIAEAQCRHSGCIN AQGQEDSTMN SVAIQQEILV LRREPQGCSN SFRLEKMLLK VGCTCVKPIV HQAA |
| Storage : | Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage. |
| Gene Name | Il17f interleukin 17F [ Mus musculus ] |
| Official Symbol | Il17f |
| Synonyms | Il17f; interleukin 17F; C87042; IL-17F |
| Gene ID | 257630 |
| mRNA Refseq | NM_145856 |
| Protein Refseq | NP_665855 |
| UniProt ID | Q7TNI7 |
| Chromosome Location | 1 A4 |
| Function | cytokine activity |
Not For Human Consumption!
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