| Species : |
Mouse |
| Source : |
NS0 |
| Tag : |
Fc |
| Description : |
Predicted to enable several functions, including chloride ion binding activity; peptide receptor activity; and protein homodimerization activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; osteoclast proliferation; and response to ischemia. Predicted to be located in plasma membrane. Predicted to be part of protein-containing complex. Is expressed in several structures, including central nervous system; gut; heart and pericardium; lung; and urinary system. Used to study bone disease. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human NPR3 (natriuretic peptide receptor 3). |
| Form : |
Disulfide-linked homodimer, Lyophilized from a 0.2 μm filtered solution in PBS. |
| Bio-activity : |
Measured by its binding ability in a functional ELISA. When Recombinant Mouse NPRC/NPR3 Fc Chimera is immobilized at 2 μg/mL (100 μL/well), the concentration of Recombinant Mouse Osteocrin that produces 50% of the optimal binding response is 0.6-3.6 ng/mL. |
| Molecular Mass : |
78 kDa |
| Endotoxin : |
< 0.10 EU/μg of the protein by the LAL method. |
| Purity : |
> 95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
| Storage : |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
| Shipping : |
The product is shipped at ambient temperature. |
| Reconstitution : |
Reconstitute at 500 μg/mL in PBS. |
| N-terminal Sequence Analysis : |
Glu41 |
