Active Recombinant Mouse Parp2, His-tagged

• Cat.No.: Parp2-453M
• Product Overview: Mouse full-length PARP-2 [ARTD2] is fused to a His-tag.

Specification

• Species: Mouse
• Source: Sf21 Cells
• Tag: His
• Description: PARP-2 [ARTD2] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
• Form: Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol.
• Bio-activity: ≥600U/mg protein.
• Purity: ≥98% (SDS-PAGE)
• Stability: Stable for at least 6 months after receipt when stored at -80°C.
• Storage: Short Term Storage: -20°C; Long Term Storage: -80°C. After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles.
• Concentration: Lot dependent (0.2-1mg/ml)

Gene Information

• Gene Name: Parp2 poly (ADP-ribose) polymerase family, member 2 [ Mus musculus ]
• Official Symbol: Parp2
• Synonyms: PARP2; poly (ADP-ribose) polymerase family, member 2; poly [ADP-ribose] polymerase 2; ADPRT-2; mPARP-2; pADPRT-2; poly[ADP-ribose] synthase 2; poly[ADP-ribose] synthetase 2; NAD(+) ADP-ribosyltransferase 2; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 2; ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2; poly(ADP-ribose) polymerase)-like 2; Adprt2; C78626; PARP-2; Adprtl2; Aspartl2
• Gene ID: 11546
• mRNA Refseq: NM_009632
• Protein Refseq: NP_033762
• Pathway: BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem
• Function: DNA binding; NAD+ ADP-ribosyltransferase activity; protein binding; transferase activity; transferase activity, transferring glycosyl groups