Active Recombinant Mouse Protein Tyrosine Phosphatase, Non-receptor Type 13

• Cat.No.: Ptpn13-337M

Specification

• Cat. No.: Ptpn13-337M
• Description: Protein Tyrosin Phosphatase, catalytic domain. Protein Tyrosine Phosphatase- Basophil-like (PTP-BL)is a large nonreceptor type protein tyrosine phosphatase characterized by the presence of a extreme N-terminal KIND domain (kinase noncatalytic C-lobe domain, a protein module identified recently that shows homology to the regulatory C-lobe of protein kinases but that lacks catalytic activity), a N-terminal FERM domain (four point one, ezrin, radixin, moesin homology domain), five PDZ (postsynaptic density protein-95, discs large, zonula occludens) regions and a C-terminal catalytically active domain. Current data suggest that PTP-BL is involved in regulation of cytoskeleton and of intracellular vesicular transport processes.
• Source: E. coli.
• Usage: For in vitro use only.
• Form: Liquid. Supplied in 20 mM Tris-HCl pH 8.0, 100 mM KCl, 0.2 mM EDTA, 1 mM DTT and 20% glycerol.
• Activity: 11 μmol/min/mg determined with pNPP as substrate at pH 7.4 and 37℃.
• Purity: > 95% by SDS-PAGE.
• Storage: Quality guaranteed for 12 months, store at -80℃. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: Ptpn13 protein tyrosine phosphatase, non-receptor type 13 [ Mus musculus ]
• Synonyms: Ptpn13; protein tyrosine phosphatase, non-receptor type 13; RIP; Ptpri; PTP-BL; AI324989; tyrosine phosphatase; EC 3.1.3.48
• Gene ID: 19249
• mRNA Refseq: NM_011204
• Protein Refseq: NP_035334
• UniProt ID: Q64512
• Function: binding; hydrolase activity; phosphatase activity; phosphoprotein phosphatase activity; protein tyrosine phosphatase activity