Active Recombinant Mouse Tnfsf14 Protein (Arg58-Val239), C-His tagged, Animal-free, Carrier-free
Cat.No. : | Tnfsf14-243M |
Product Overview : | Recombinant Mouse Tnfsf14 Protein (Arg58-Val239) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Mouse |
Source : | E.coli |
Tag : | His |
Protein Length : | Arg58-Val239 |
Description : | LIGHT, also known as TNFSF14 is a member of the TNF superfamily that produced by multiple immune cells such as activated T cells and immature dendritic cells (DCs). Mouse LIGHT shares 79% sequence homology with human LIGHT. LIGHT is a 29 kDa type II transmembrane protein, which serves as a ligand for both lymphotoxin β receptor (LTβR) and TNFSF signaling receptors (TNFRSF14/HVEM). Besides, LIGHT can amplify NF-kB signaling pathway in T cells when presencing anti-CD3 antibody treatment. Additionally, LIGHT is able to stimulate T cell proliferation and IFN expression via interacting with TNFRS13 /HVEM. |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to induce cytotoxicity in HT-29 cells. The ED50 for this effect is < 2 μg/mL. |
Molecular Mass : | The protein has a calculated MW of 20.92 kDa. The protein migrates about 17 kDa under reducing condition (SDS-PAGE analysis). |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >98% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name | Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 [ Mus musculus (house mouse) ] |
Official Symbol | Tnfsf14 |
Synonyms | TNFSF14; tumor necrosis factor (ligand) superfamily, member 14; tumor necrosis factor ligand superfamily member 14; LTg; HVEML; LIGHT; Ly113; HVEM-L; |
Gene ID | 50930 |
mRNA Refseq | NM_019418 |
Protein Refseq | NP_062291 |
UniProt ID | Q9QYH9 |
◆ Recombinant Proteins | ||
TNFSF14-5236H | Recombinant Human TNFSF14 Protein (Leu59-Val240), N-His tagged | +Inquiry |
TNFSF14-217H | Recombinant Human TNFSF14 protein, His-tagged | +Inquiry |
TNFSF14-552HAF555 | Recombinant Human TNFSF14 Protein, hFc-tagged, Alexa Fluor 555 conjugated | +Inquiry |
TNFSF14-783C | Recombinant Cynomolgus Monkey TNFSF14 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFSF14-552H | Recombinant Human TNFSF14 protein, Fc-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
TNFSF14-891HCL | Recombinant Human TNFSF14 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews (0)
- Q&As (0)
Ask a Question for All Tnfsf14 Products
Required fields are marked with *
My Review for All Tnfsf14 Products
Required fields are marked with *
0
Inquiry Basket