Active Recombinant Mouse Tnfsf4, FLAG-tagged

• Cat.No.: Tnfsf4-407M
• Product Overview: The extracellular domain of mouse OX40L (aa 52-199) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG-tag.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Flag
• Protein Length: 52-199;18-111 a.a.
• Description: OX40L [CD252; CD134L] is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium. MegaOX40L is a high activity construct in which two trimeric OX40L ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively activates T cell proliferation.
• Form: Lyophilized. Contains PBS.
• Bio-activity: Activates T cell proliferation.
• Molecular Mass: ~40kDa (SDS-PAGE)
• Purity: ≥90% (SDS-PAGE)
• Stability: Stable for at least 6 months after receipt when stored at -20°C.
• Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
• Concentration: 0.1mg/ml after reconstitution.

Gene Information

• Gene Name: Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 [ Mus musculus ]
• Official Symbol: Tnfsf4
• Synonyms: TNFSF4; tumor necrosis factor (ligand) superfamily, member 4; tumor necrosis factor ligand superfamily member 4; OX40 ligand; atherosclerosis 1; tax-transcriptionally activated glycoprotein 1 ligand; Ath1; gp34; Ath-1; Ox40l; TXGP1; CD134L; OX-40L; Txgp1l
• Gene ID: 22164
• mRNA Refseq: NM_009452
• Protein Refseq: NP_033478
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: cytokine activity; tumor necrosis factor receptor binding; tumor necrosis factor receptor superfamily binding; tumor necrosis factor receptor superfamily binding