Active Recombinant Mouse TTBK2, GST-tagged

• Cat.No.: TTBK2-1502M
• Product Overview: Recombinant mouse TTBK2 (70-538) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: TTBK2 or tau tubulin kinase 2 is a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. TTBK2 is a member of the casein kinase (CK1) group of eukaryotic protein kinases that is involved in tau phosphorylation and aggregation. Mutations in TTBK2 cause spinocerebellar ataxia type 11 (SCA11) (a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem).
• Source: Sf9 Cells
• Species: Mouse
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Bio-activity: 370 nmol/min/mg
• Molecular Mass: ~88 kDa
• Protein length: 70-538 aa
• Purity: >95%
• Applications: Kinase Assay, Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.1μg/μl

Gene Information

• Gene Name: Ttbk2 tau tubulin kinase 2 [ Mus musculus ]
• Official Symbol: TTBK2
• Synonyms: TTBK2; tau tubulin kinase 2; tau-tubulin kinase 2; TTK; Ttbk; Ttbk1; AI326283; mKIAA0847; 2610507N02Rik; B930008N24Rik; KIAA0847
• Gene ID: 140810
• mRNA Refseq: NM_001024856
• Protein Refseq: NP_001020027
• Function: ATP binding; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups